JTE 607 dihydrochloride (ab273390)
Key features and details
- Cytokine release inhibitor
- CAS Number: 188791-09-5
- Purity: > 98%
Soluble in DMSO to 100 mM and water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
JTE 607 dihydrochloride -
描述
Cytokine release抑制剂 -
生物学描述
Inhibits inflammatory cytokine production in human peripheral blood mononuclear cells (PBMC’s), e.g. IC50’s = 11 nM (TNF-α), 5.9 nM (IL-1β), 8.8 nM (IL-6), 7.3 nM (IL-8), and 9.1 nM (IL-10). Induces apoptosis in leukemia cells in vitro and prolongs survival in a mouse leukemia model.
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纯度
> 98% -
CAS编号
188791-09-5 -
化学结构
性能
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化学名称
Ethyl ester-N-[3,5-dichloro-2-hydroxy-4-[2-(4-methyl-1- piperazinyl)ethoxy]benzoyl]-L-phenylalanine, dihydrochloride
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分子量
597.36 -
分子式
C23H33Cl2N3O5.2HCl -
PubChem识别号
9938544 -
存放说明
Shipped at 4°C. Store at -20°C. -
溶解度概述
Soluble in DMSO to 100 mM and water to 100 mM
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处理
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCOC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=CC(=C(C(=C2O)Cl)OCCN3CCN(CC3)C)Cl.Cl.Cl -
来源
Synthetic
图片
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Chemical Structure - JTE 607 dihydrochloride (ab273390)
Chemical structure of JTE 607 dihydrochloride, 188791-09-5
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab273390 尚未被引用在任何文献中。
