Iodotubercidin，adenosine kinase抑制剂(ab120452)
Key features and details
- Potent, adenosine kinase inhibitor
- CAS Number: 24386-93-4
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Iodotubercidin，adenosine kinase抑制剂 -
描述
Potent，adenosine kinase抑制剂 -
生物学描述
Potent, specific adenosine kinase inhibitor (IC50 = 26 nM). Inhibits platelet aggregation and spreading, and interferes with adenosine and adenine nucleotide metabolism. Additionally inhibits other kinases such as ERK2 (Ki = 525 nM).
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CAS编号
24386-93-4 -
化学结构
性能
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化学名称
5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine -
分子量
392.15 -
分子式
C11H13IN4O4 -
PubChem识别号
46875276 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 50 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Nc3ncnc2c3c(I)cn2C1O[C@H](CO)[C@@H](O)[C@H]1O -
来源
Synthetic
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研究领域
图片
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Chemical Structure - Iodotubercidin, adenosine kinase inhibitor (ab120452)2D chemical structure image of ab120452, Iodotubercidin, adenosine kinase inhibitor
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (1)
ab120452 被引用在 1 文献中.
- Huang L et al. Enhanced expression of WD repeat-containing protein 35 via CaMKK/AMPK activation in bupivacaine-treated Neuro2a cells. PLoS One 9:e98185 (2014). PubMed: 24859235