IBMX，Non-specific cAMP and cGMP抑制剂(ab120840)
Key features and details
- Non-specific cAMP and cGMP inhibitor
- CAS Number: 28822-58-4
- Purity: > 98%
- Soluble in DMSO to 75 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
IBMX，Non-specific cAMP and cGMP抑制剂 -
描述
Non-specific cAMP and cGMP抑制剂 -
纯度
> 98% -
CAS编号
28822-58-4 -
化学结构
性能
-
化学名称
1-Methyl-3-(2-methylpropyl)-7H-purine-2,6-dione -
分子量
222.24 -
分子式
C10H14N4O2 -
PubChem识别号
3758 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 75 mM and in ethanol to 50 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC(C)CN1C2=C(C(=O)N(C1=O)C)NC=N2 -
来源
Synthetic
-
研究领域
图片
-
Chemical Structure - IBMX, Non-specific cAMP and cGMP inhibitor (ab120840)2D chemical structure image of ab120840, IBMX, Non-specific cAMP and cGMP inhibitor
-
Functional Studies - IBMX, Non-specific cAMP and cGMP inhibitor (ab120840)1e7 3T3-L1 cells were treated for 15 minutes with 1 µM dexamethasone (ab120743) and 1 µg x mL-1 insulin (ab123768) with the addition of 50 µM forskolin (ab120058), 0.5 mM IBMX (ab120840) or 0.1 mM 8-CPT-cAMP (ab120424), extracted according to the protocol. Lysates were diluted 50-fold, and tested in duplicates (+/-SD).
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab120840 被引用在 1 文献中.
- Wang P et al. Disruption of adipocyte HIF-1α improves atherosclerosis through the inhibition of ceramide generation. Acta Pharm Sin B 12:1899-1912 (2022). PubMed: 35847503