Guanosine 3',5'-cyclic monophosphate sodium salt (cGMP),cyclic nucleotide second messenger (ab120805)
Key features and details
- Cyclic nucleotide second messenger
- CAS Number: 40732-48-7
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Guanosine 3',5'-cyclic monophosphate sodium salt (cGMP),cyclic nucleotide second messenger -
描述
Cyclic nucleotide second messenger -
别名
- cGMP
- Cyclic GMP
- Guanosine 3',5'-cyclic monophosphate
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生物学描述
Cyclic nucleotide second messenger derived from guanosine triphosphate. Generated by guanylate cyclases. Involved in a number of cellular processes; downstream targets include cyclic nucleotide gated channels, cGMP-regulated phosphodiesterases and cGMP-dependent kinases.
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纯度
> 99% -
CAS编号
40732-48-7 -
化学结构
性能
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化学名称
Guanosine 3',5'-cyclophosphate sodium salt -
分子量
367.19 -
分子式
C10H11N5NaO7P -
PubChem识别号
23702131 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
NC4=Nc3c(ncn3C2O[C@@H]1COP(=O)(O[C@H]1[C@H]2O)O[Na])C(=O)N4 -
来源
Synthetic
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研究领域
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab120805 被引用在 3 文献中.
- Davies SA Signalling via cGMP: lessons from Drosophila. Cell Signal 18:409-21 (2006). PubMed: 16260119
- Krumenacker JS & Murad F NO-cGMP signaling in development and stem cells. Mol Genet Metab 87:311-4 (2006). PubMed: 16356747
- Feil R et al. Function of cGMP-dependent protein kinases in the nervous system. Rev Neurosci 16:23-41 (2005). PubMed: 15810652