Gossypin，Chk1/Cdc25C活化剂

关键信息

CAS 号

652-78-8

纯度

>98%

形式

Solid

form

来源

Hibiscus vitifolius

分子量

480.4 Da

分子式

C₂₁H₂₀O₁₃

PubChem

5281621

属性

Native

溶解度

Soluble in DMSO to 25 mM

生化试剂名称

Gossypin

生物学描述

Chk1/Cdc25C activator. Antioxidant agent. Induces G2/M cell cycle arrest. Reduces lipid peroxidation. Shows antitumor, anti-ischemic and neuroprotective effects in vivo. Orally active.

经典 SMILES

C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O)O

同分异构的 SMILES

C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O)O

InChi

InChI=1S/C21H20O13/c22-5-11-13(27)15(29)17(31)21(32-11)34-19-10(26)4-9(25)12-14(28)16(30)18(33-20(12)19)6-1-2-7(23)8(24)3-6/h1-4,11,13,15,17,21-27,29-31H,5H2/t11-,13-,15+,17-,21+/m1/s1

InChiKey

SJRXVLUZMMDCNG-KKPQBLLMSA-N

IUPAC 名

2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one