gamma-DGG (gamma-D-Glutamylglycine)，Ionotropic glutamate拮抗剂(ab120307)
Key features and details
- Ionotropic glutamate antagonist. Low affinity AMPA antagonist.
- CAS Number: 6729-55-1
- Purity: > 98%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
gamma-DGG (gamma-D-Glutamylglycine)，Ionotropic glutamate拮抗剂 -
描述
Ionotropic glutamate拮抗剂. Low affinity AMPA拮抗剂. -
别名
- γ-D-Glutamylglycine
-
生物学描述
Ionotropic glutamate receptor antagonist that has been used as a rapidly dissociating, low affinity competitive antagonist at AMPA receptors.
Also available in simple stock solutions (ab146702) - add 1 ml of water to get an exact, ready-to-use concentration. -
纯度
> 98% -
CAS编号
6729-55-1 -
化学结构
性能
-
化学名称
(R)-4-(Carboxymethylcarbamoyl)-2-aminobutanoic acid -
分子量
204.18 -
分子式
C7H12N2O5 -
PubChem识别号
6604701 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
O=C(CC[C@@H](N)C(=O)O)NCC(=O)O -
来源
Synthetic
-
研究领域
图片
-
Chemical Structure - gamma-DGG (gamma-D-Glutamylglycine), Ionotropic glutamate antagonist (ab120307)2D chemical structure image of ab120307, gamma-DGG (gamma-D-Glutamylglycine), Ionotropic glutamate antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (3)
ab120307 被引用在 3 文献中.
- Van Hook MJ Brain-derived neurotrophic factor is a regulator of synaptic transmission in the adult visual thalamus. J Neurophysiol 128:1267-1277 (2022). PubMed: 36224192
- Biane C et al. Developmental emergence of two-stage nonlinear synaptic integration in cerebellar interneurons. Elife 10:N/A (2021). PubMed: 34730085
- Bornschein G et al. Neocortical High Probability Release Sites Are Formed by Distinct Ca2+ Channel-to-Release Sensor Topographies during Development. Cell Rep 28:1410-1418.e4 (2019). PubMed: 31390556
