Evans blue，L-glutamate uptake抑制剂(ab120869)
Key features and details
- Potent inhibitor of L-glutamate uptake
- CAS Number: 314-13-6
- Purity: > 95%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Evans blue，L-glutamate uptake抑制剂 -
描述
Potent抑制剂of L-glutamate uptake -
别名
- EAA2_HUMAN
- EAAT2
- Excitatory amino acid transporter 2
see all -
生物学描述
Potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Able to antagonize AMPA and kainate receptor mediated currents (IC50 values are 220 and 150 nM, respectively). Binds with high affinity to serum albumin.
Also available in simple stock solutions (ab146727) - add 1 ml of water to get an exact, ready-to-use concentration. -
纯度
> 95% -
CAS编号
314-13-6 -
化学结构
性能
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化学名称
6,6'-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[4-amino-5-hydroxy-1,3-naphthalenedisulfonic acid] tetrasodium salt -
分子量
960.80 -
分子式
C34H24N6Na4O14S4 -
PubChem识别号
9566057 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=S(=O)(O[Na])c6cc(c(N)c5c6ccc(/N=N/c1ccc(cc1C)c4ccc(/N=N/c3ccc2c(cc(c(N)c2c3O)S(=O)(=O)O[Na])S(=O)(=O)O[Na])c(C)c4)c5O)S(=O)(=O)O[Na] -
来源
Synthetic
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研究领域
图片
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Chemical Structure - Evans blue, L-glutamate uptake inhibitor (ab120869)2D chemical structure image of ab120869, Evans blue, L-glutamate uptake inhibitor
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (2)
ab120869 被引用在 2 文献中.
- Liu Y et al. Evidence of Accumulated Endothelial Progenitor Cells in the Lungs of Rats with Pulmonary Arterial Hypertension by 89Zr-oxine PET Imaging. Mol Ther Methods Clin Dev 17:1108-1117 (2020). PubMed: 32490032
- Wu J et al. Genetic stability of a recombinant adenovirus vaccine vector seed library expressing human papillomavirus type 16 E6 and E7 proteins. Exp Ther Med 9:1161-1165 (2015). IF ; Human . PubMed: 25780403