Endothelin-1 (human，porcine)，Vasoconstrictor多肽(ab120471)
Key features and details
- Vasoconstrictor peptide
- CAS Number: 117399-94-7
- Soluble in 1% acetic acid to 1mg/ml
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
Endothelin-1 (human，porcine)，Vasoconstrictor多肽 -
描述
Vasoconstrictor多肽 -
生物学描述
Endogenous agonist at ETA and ETB receptors. Potent vasoconstrictor peptide involved in modulating vascular tone.
-
CAS编号
117399-94-7 -
化学结构
性能
-
分子量
2491.90 -
分子式
C109H159N25O32S5 -
序列
CSCSSLMDKECVYFCHLDIIW (Modifications: Disulfide bonds: 1-15, 3-11) -
PubChem识别号
16133807 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in 1% acetic acid to 1mg/ml -
处理
This product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3=CNC=N3)NC(=O)[C@@H]4CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H]5CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N4)CC6=CC=CC=C6)CC7=CC=C(C=C7)O)C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC5=O)CO)CO)CC(C)C)CCSC)CC(=O)O)CCCCN)CCC(=O)O)CO)N -
来源
Synthetic
-
研究领域
图片
-
Chemical Structure - Endothelin-1 (human, porcine), Vasoconstrictor peptide (ab120471)2D chemical structure image of ab120471, Endothelin-1 (human, porcine), Vasoconstrictor peptide
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (8)
ab120471 被引用在 8 文献中.
- Cappelli J et al. Glycine-induced NMDA receptor internalization provides neuroprotection and preserves vasculature following ischemic stroke. iScience 25:103539 (2022). PubMed: 34977503
- Martin M et al. Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders. Science 375:eabm4459 (2022). PubMed: 35175798
- Schuch CP et al. An RFID-based activity tracking system to monitor individual rodent behavior in environmental enrichment: Implications for post-stroke cognitive recovery. J Neurosci Methods 324:108306 (2019). PubMed: 31152754
- Obermeyer JM et al. Local Delivery of Brain-Derived Neurotrophic Factor Enables Behavioral Recovery and Tissue Repair in Stroke-Injured Rats. Tissue Eng Part A 25:1175-1187 (2019). PubMed: 30612516
- Sander KN et al. Pharmacological profile of vascular activity of human stem villous arteries. Placenta 88:12-19 (2019). PubMed: 31574379
- Balbinot G et al. Post-stroke kinematic analysis in rats reveals similar reaching abnormalities as humans. Sci Rep 8:8738 (2018). PubMed: 29880827
- Jeffers MS et al. Does Stroke Rehabilitation Really Matter? Part B: An Algorithm for Prescribing an Effective Intensity of Rehabilitation. Neurorehabil Neural Repair 32:73-83 (2018). PubMed: 29334831
- Jeffers MS & Corbett D Synergistic Effects of Enriched Environment and Task-Specific Reach Training on Poststroke Recovery of Motor Function. Stroke 49:1496-1503 (2018). PubMed: 29752347