DPN，ERbeta激动剂(ab120166)
Key features and details
- Potent, selective ERβ agonist
- CAS Number: 1428-67-7
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
DPN，ERbeta激动剂 -
描述
Potent，selective ERβ激动剂 -
生物学描述
Potent, selective ERβ agonist (EC50 values are 0.85 and 66 nM for ERβ and ERα, respectively). Cardioprotective and neuroprotective in vivo.
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CAS编号
1428-67-7 -
化学结构
性能
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化学名称
2,3-Bis(4-hydroxyphenyl)propionitrile -
分子量
239.27 -
分子式
C15H13NO2 -
PubChem识别号
102614 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Oc1ccc(cc1)C(Cc2ccc(O)cc2)C#N -
来源
Synthetic
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研究领域
图片
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Chemical Structure - DPN, ERbeta agonist (ab120166)2D chemical structure image of ab120166, DPN, ERbeta agonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (1)
ab120166 被引用在 1 文献中.
- Oh YS et al. ESR1 inhibits hCG-induced steroidogenesis and proliferation of progenitor Leydig cells in mice. Sci Rep 7:43459 (2017). PubMed: 28266530