DPCPX，A1拮抗剂(ab120396)
Key features and details
- Potent A1 antagonist
- CAS Number: 102146-07-6
- Soluble in ethanol to 10 mM and in DMSO to 5 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
DPCPX，A1拮抗剂 -
描述
Potent A1拮抗剂 -
生物学描述
Potent A1antagonist (Ki = 0.45 nM). Also exhibits antagonism at A2B receptors (pA2 = 7.16, for human A2B expressed in CHO cells).
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CAS编号
102146-07-6 -
化学结构
性能
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化学名称
8-Cyclopentyl-1,3-dipropylxanthine -
分子量
304.39 -
分子式
C16H24N4O2 -
PubChem识别号
1329 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in ethanol to 10 mM and in DMSO to 5 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C2c1nc(nc1N(CCC)C(=O)N2CCC)C3CCCC3 -
来源
Synthetic
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研究领域
图片
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Chemical Structure - DPCPX, A1 antagonist (ab120396)2D chemical structure image of ab120396, DPCPX, A1 antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (13)
ab120396 被引用在 13 文献中.
- Wang W et al. Inhibition of adenosine kinase attenuates myocardial ischaemia/reperfusion injury. J Cell Mol Med 25:2931-2943 (2021). PubMed: 33523568
- Lv YC et al. Long-term adenosine A1 receptor activation-induced sortilin expression promotes a-synuclein upregulation in dopaminergic neurons. Neural Regen Res 15:712-723 (2020). PubMed: 31638096
- Yi X et al. Adenosine receptors enhance the ATP-induced odontoblastic differentiation of human dental pulp cells. Biochem Biophys Res Commun 497:850-856 (2018). PubMed: 29454963
- Kashfi S et al. Purinergic Receptor Expression and Potential Association with Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cell Development. Cell J 19:386-402 (2017). PubMed: 28836401
- Zhou Y et al. The Adenosine A1 Receptor Antagonist DPCPX Inhibits Tumor Progression via the ERK/JNK Pathway in Renal Cell Carcinoma. Cell Physiol Biochem 43:733-742 (2017). PubMed: 28950257