DL-AP5 sodium salt，NMDA glutamate site拮抗剂(ab120271)
Key features and details
- NMDA glutamate site antagonist. Water soluble form.
- CAS Number: 1303993-72-7
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
DL-AP5 sodium salt，NMDA glutamate site拮抗剂 -
描述
NMDA glutamate site拮抗剂. Water soluble form. -
生物学描述
Competitive NMDA receptor glutamate site antagonist. Water soluble form.
Also available in simple stock solutions (ab144498) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS编号
1303993-72-7 -
化学结构
性能
-
化学名称
DL-2-Amino-5-phosphonopentanoic acid sodium salt -
分子量
219.11 -
分子式
C5H11NNaO5P -
PubChem识别号
52974251 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
O=P(O)(CCCC(N)C(=O)O)O[Na] -
来源
Synthetic
-
研究领域
图片
-
Chemical Structure - DL-AP5 sodium salt, NMDA glutamate site antagonist (ab120271)2D chemical structure image of ab120271, DL-AP5 sodium salt, NMDA glutamate site antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (27)
ab120271 被引用在 27 文献中.
- Bonnycastle K et al. Reversal of cell, circuit and seizure phenotypes in a mouse model of DNM1 epileptic encephalopathy. Nat Commun 14:5285 (2023). PubMed: 37648685
- Chou MY et al. Mir125b-2 imprinted in human but not mouse brain regulates hippocampal function and circuit in mice. Commun Biol 6:267 (2023). PubMed: 36918719
- Kontaxi C et al. Epilepsy-Related CDKL5 Deficiency Slows Synaptic Vesicle Endocytosis in Central Nerve Terminals. J Neurosci 43:2002-2020 (2023). PubMed: 36759195
- Cheng J et al. Loss of O-GlcNAcylation on MeCP2 at Threonine 203 Leads to Neurodevelopmental Disorders. Neurosci Bull 38:113-134 (2022). PubMed: 34773221
- Bonnycastle K et al. FMRP Sustains Presynaptic Function via Control of Activity-Dependent Bulk Endocytosis. J Neurosci 42:1618-1628 (2022). PubMed: 34996816
