DL-AP5，NMDA glutamate site拮抗剂(ab120004)
Key features and details
- NMDA glutamate site antagonist
- CAS Number: 76326-31-3
- Purity: > 99%
- Soluble in water to 25 mM and in 1 eq. NaOH to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
DL-AP5，NMDA glutamate site拮抗剂 -
描述
NMDA glutamate site拮抗剂 -
生物学描述
Competitive NMDA receptor glutamate site antagonist. Also available as the sodium salt (ab120271).
-
纯度
> 99% -
CAS编号
76326-31-3 -
化学结构
性能
-
化学名称
DL-2-Amino-5-phosphonopentanoic acid -
分子量
197.13 -
分子式
C5H12NO5P -
PubChem识别号
1216 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 25 mM and in 1 eq. NaOH to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
NC(CCCP(=O)(O)O)C(=O)O -
来源
Synthetic
-
研究领域
图片
-
Chemical Structure - DL-AP5, NMDA glutamate site antagonist (ab120004)2D chemical structure image of ab120004, DL-AP5, NMDA glutamate site antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (81)
ab120004 被引用在 81 文献中.
- Asgarihafshejani A et al. Long-term potentiation at pyramidal cell to somatostatin interneuron synapses controls hippocampal network plasticity and memory. iScience 25:104259 (2022). PubMed: 35521524
- Martín-de-Saavedra MD et al. Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2. Neuron 110:627-643.e9 (2022). PubMed: 34921780
- Zaccard CR et al. Protocol for live enhanced resolution confocal imaging of dendritic spinule dynamics in primary mouse cortical neuron culture. STAR Protoc 2:100427 (2021). PubMed: 33899014
- Zaccard CR et al. Rapid 3D Enhanced Resolution Microscopy Reveals Diversity in Dendritic Spinule Dynamics, Regulation, and Function. Neuron 107:522-537.e6 (2020). PubMed: 32464088
- Erli F et al. Estradiol reverses excitatory synapse loss in a cellular model of neuropsychiatric disorders. Transl Psychiatry 10:16 (2020). PubMed: 32066698