Dexamethasone, anti-inflammatory glucocorticoid

Dexamethasone, anti-inflammatory glucocorticoid

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(3 Publications)

MW 392.5 Da, Purity >99%. Anti-inflammatory glucocorticoid (IC₅₀ = 38 nM and K_i = 6.7 nM for the glucocorticoid receptor). Displays 7-fold higher affinity for glucocorticoid receptors than hydrocortisone. Long-term effects following oral administration. Used in the generation of liver organoids.

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(R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, ABC 35, ABCC 7, ATP Binding Cassette Superfamily C Member 7, ATP binding cassette transporter sub family C member 7, ATP-binding cassette sub-family C member 7, Avian reticuloendotheliosis viral (v rel) oncogene homolog A, BAR, BXR, Bile acid receptor, CF, CFTR/MRP, CFTR_HUMAN, CIMT1, CP2C9_HUMAN, CP2D6_HUMAN, CPC9, CPD6, CYP2C, CYP2C10, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIIC9, CYPIID6, Channel conductance-controlling ATPase, Cholesterol 25-hydroxylase, Cystic Fibrosis Transmembrane Regulator, Cystic fibrosis transmembrane conductance regulator, Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub family C, member 7), Cystic fibrosis transmembrane conductance regulator ATP binding cassette sub family C member 7, Cytochrome P-450MP, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 MP-4, Cytochrome P450 MP-8, Cytochrome P450 PB-1, Cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 family 2 subfamily D polypeptide 6, Cytochrome P450, family 2, subfamily C, polypeptide 9, Cytochrome P450-DB1, Debrisoquine 4-hydroxylase, FABP 1, FABPL_HUMAN, FXR, Farnesoid X receptor, Farnesoid X-activated receptor, Farnesol receptor HRR-1, Fatty acid binding protein 1 liver, Fatty acid-binding protein, Fatty acid-binding protein 1, Fatty acid-binding protein liver, GLM1, HRR 1, L-FABP, Liver-type fatty acid-binding protein, MGC131774, MGC149605, MGC88320, Microsomal monooxygenase, NF kappa B p65delta3, NFKB3, NFkB p65, NR1C3, NR1H4_HUMAN, NR1I2_HUMAN, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor kappa-B, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, Nuclear receptor subfamily 1 group C member 3, Nuclear receptor subfamily 1 group H member 4, Nuclear receptor subfamily 1 group I member 2, ONR 1, OTTHUMP00000020135, OTTHUMP00000185032, OTTHUMP00000185036, OTTHUMP00000215173, OTTHUMP00000215174, OTTHUMP00000215175, OTTHUMP00000233473, OTTHUMP00000233474, OTTHUMP00000233475, OTTHUMP00000233476, OTTHUMP00000233900, Orphan nuclear receptor PAR 1, Orphan nuclear receptor PXR, P450 DB1, P450 MP, P450 PB 1, P450C2D, P450IIC9, PAR, PAR q, PPAR-gamma, PPARG1, PPARG2, PPARG_HUMAN, PRR, Peroxisome proliferator activated nuclear receptor gamma variant 1, Peroxisome proliferator activated receptor gamma 1, Peroxisome proliferator-activated receptor gamma, Pregnane X receptor, RIP 14, RXR-interacting protein 14, Retinoid X receptor-interacting protein 14, S-mephenytoin 4-hydroxylase, SXR, Steroid and xenobiotic receptor, TF65_HUMAN, TNR CFTR, Transcription factor NFKB3, Transcription factor p65, V rel avian reticuloendotheliosis viral oncogene homolog A, V rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B cells 3, p65, Xenobiotic monooxygenase, cAMP-dependent chloride channel, cytochrome P-450 S-mephenytoin 4-hydroxylase, dJ760C5.1, flavoprotein-linked monooxygenase, nfkappabp65, p65, p65 NF kappaB, p65 NFkB, pregnane X nuclear receptor variant 2, relA, v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)), v rel reticuloendotheliosis viral oncogene homolog A (avian)