AB285390

DAPI

Name: DAPI (ab285390)| Abcam中文官网
Brand: Abcam Limited
SKU: AB285390
Price: 1256 CNY
Availability: InStock

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(58 Publications)

DAPI (ab285390) is a fluorescent, cell-permeable DNA-binding dye and preferentially binds to DNA rich in adenine and thymine. Suitable to use for fluorescence microscopy. DAPI's absorption maximum when bound to double-stranded DNA is at 358 nm and its emission maximum is at 461 nm. MW 350.2, Purity >98%.

- Proven performance: cited in over 55 publications
- Convenient for multiplexing assays as little overlap between green- and red- fluorescence molecules
- Available in different sizes to fit your experimental needs

关键信息

CAS 号

28718-90-3

纯度

>98%

形式

Solid

form

分子量

350.2 Da

分子式

C16H17Cl2N5

PubChem

160166

属性

Synthetic

溶解度

DMSO (>35 mg/ml)

生化试剂名称

2-(4-Carbamimidoylphenyl)-1h-indole-6-carboximidamide dihydrochloride

生物学描述

A fluorescent, cell-permeable DNA-binding dye. Preferentially binds to DNA rich in adenine and thymine.

经典 SMILES

C1=CC(=CC=C1C2=CC3=C(N2)C=C(C=C3)C(=N)N)C(=N)N.Cl.Cl

InChi

InChI=1S/C16H15N5.2ClH/c17-15(18)10-3-1-9(2-4-10)13-7-11-5-6-12(16(19)20)8-14(11)21-13;;/h1-8,21H,(H3,17,18)(H3,19,20);2*1H

InChiKey

FPNZBYLXNYPRLR-UHFFFAOYSA-N

IUPAC 名

2-(4-carbamimidoylphenyl)-1H-indole-6-carboximidamide;dihydrochloride

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产品详情

This product is manufactured by BioVision, an Abcam company and was previously called B1098 DAPI. B1098-5 is the same size as the 5 mg size of ab285390.

Protect from air and light.

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性能和储存信息

运输条件

Blue Ice

储存信息

It is important to note that this is air sensitive and impurities can occur as a result of air oxidation|Store in the dark

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产品实验方案

Visit the General protocols
Visit the Troubleshooting

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文献 (58)

Recent publications for all applications. Explore the full list and refine your search

Chemical biology & drug design 105:e70133 PubMed40490914

2025

Ferulic Acid Inhibits Partial Epithelial-Mesenchymal Transition in Renal Tubular Epithelial Cells and Mitigates Renal Interstitial Fibrosis by Regulating the HIF-1α/Twist Signaling Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Lin Xu,Dongsheng Yao,Tianying Lan,Yurou Chen,Dongping Chen,Minghai Shao,Yijing Zhou,Chaoyang Ye,Di Huang

Molecular medicine (Cambridge, Mass.) 31:168 PubMed40325385

2025

Inhibition of TLR4 mitigates sensorineural hearing loss resulting from cochlear inflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Jintao Lou,Fan Wu,Wei Liu,Rui Hu,Wuhui He,Yisi Feng,Yan Huang,Jia Guo,Jingman Deng,Zhen Zhao,Zhigang Zhang,Yu Si

MedComm 6:e70138 PubMed40264576

2025

Integrating Multiplex Immunohistochemistry and Machine Learning for Glioma Subtyping and Prognosis Prediction.

Applications

Unspecified application

Species

Unspecified reactive species

Houshi Xu,Zhen Fan,Shan Jiang,Maoyuan Sun,Huihui Chai,Ruize Zhu,Xiaoyu Liu,Yue Wang,Jiawen Chen,Junji Wei,Ying Mao,Zhifeng Shi

CNS neuroscience & therapeutics 31:e70368 PubMed40202077

2025

TRPC4 Mediates Trigeminal Neuropathic Pain via Ca-ERK/P38-ATF2 Pathway in the Trigeminal Ganglion of Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Xinlong Ke,Huajing Cai,Fangla Luo,Xing Zheng,Qian Hu,Youfa Zhou,Yongjie Wang,Xiangnan Zhang,Yeru Chen,Gang Chen

Journal of nanobiotechnology 23:282 PubMed40197477

2025

Microenvironment-adaptive nanomedicine MXene promotes flap survival by inhibiting ROS cascade and endothelial pyroptosis.

Applications

Unspecified application

Species

Unspecified reactive species

Ningning Yang,Rongrong Hua,Yingying Lai,Peijun Zhu,Jian Ding,Xianhui Ma,Gaoxiang Yu,Yiheng Xia,Chao Liang,Weiyang Gao,Zhouguang Wang,Hongyu Zhang,Liangliang Yang,Kailiang Zhou,Lu Ge

Stem cell research & therapy 16:148 PubMed40140882

2025

Exosomes derived from a mesenchymal-like endometrial regenerative cells ameliorate renal ischemia reperfusion injury through delivery of CD73.

Applications

Unspecified application

Species

Unspecified reactive species

Bo Shao,Hong-da Wang,Shao-Hua Ren,Qiang Chen,Zhao-Bo Wang,Yi-Ni Xu,Tong Liu,Cheng-Lu Sun,Yi-Yi Xiao,Hong-Yu Jiang,Yi-Cheng Li,Peng-Yu Zhao,Guang-Mei Yang,Xu Liu,Yu-Fan Ren,Hao Wang

Frontiers in cellular and infection microbiology 14:1413018 PubMed40104260

2025

Significance of the gut tract in the therapeutic mechanisms of polydopamine for acute cerebral infarction: neuro-immune interaction through the gut-brain axis.

Applications

Unspecified application

Species

Unspecified reactive species

Feng-Hua Xu,Xiao Sun,Jun Zhu,Ling-Yang Kong,Yuan Chang,Ning Li,Wen-Xiang Hui,Cong-Peng Zhang,Yi-Ming Cheng,Wen-Xin Han,Zhi-Min Tian,Yan-Ning Qiao,Dong-Feng Chen,Lei Liu,Da-Yun Feng,Jing Han

International journal of medical sciences 22:1602-1611 PubMed40093806

2025

Escin Rescues Blood-brain Barrier and Inhibits NLRP3 Inflammasome-mediated Pyroptosis in Rats with Superior Sagital Sinus Thrombosis.

Applications

Unspecified application

Species

Unspecified reactive species

Min Li,Xinjian Liu,Xinyu Zhou,Ran Meng,Xunming Ji

European journal of medical research 30:144 PubMed40022250

2025

The mechanism of high mobility group box-1 in the proliferation and macrophage polarization in esophageal squamous cell carcinoma cells.

Applications

Unspecified application

Species

Unspecified reactive species

Liling Luo,Chao Jiang,Songxi Xie

Life metabolism 3:loae026 PubMed39873005

2025

Phytic acid-based nanomedicine against mTOR represses lipogenesis and immune response for metabolic dysfunction-associated steatohepatitis therapy.

Applications

Unspecified application

Species

Unspecified reactive species

Fenghua Xu,Shoujie Zhao,Yejing Zhu,Jun Zhu,Lingyang Kong,Huichen Li,Shouzheng Ma,Bo Wang,Yongquan Qu,Zhimin Tian,Junlong Zhao,Lei Liu

View all publications

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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

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For licensing inquiries, please contact partnerships@abcam.com

DAPI

DAPI

关键信息

CAS 号

纯度

形式

分子量

分子式

PubChem

属性

溶解度

生化试剂名称

生物学描述

经典 SMILES

InChi

InChiKey

IUPAC 名