D-Cycloserine,NMDA glycine site激动剂(ab120121)
Key features and details
- NMDA glycine site agonist
- CAS Number: 68-41-7
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
D-Cycloserine,NMDA glycine site激动剂 -
描述
NMDA glycine site激动剂 -
生物学描述
Partial agonist at the NMDA receptor glycine recognition site. Enhances learning and memory in vivo. Perfomance enhancer in a variety of cognitive models.
Also available in simple stock solutions (ab146677) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS编号
68-41-7 -
化学结构
性能
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化学名称
(R)-4-Aminoisoxazolidin-3-one -
分子量
102.09 -
分子式
C3H6N2O2 -
PubChem识别号
6234 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
N[C@@H]1CONC1=O -
来源
Synthetic
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab120121 被引用在 3 文献中.
- Kim NS et al. CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders. Biol Psychiatry 92:815-826 (2022). PubMed: 34247782
- Shih PY et al. CTTNBP2 Controls Synaptic Expression of Zinc-Related Autism-Associated Proteins and Regulates Synapse Formation and Autism-like Behaviors. Cell Rep 31:107700 (2020). PubMed: 32492416
- Huang TN et al. Interhemispheric Connectivity Potentiates the Basolateral Amygdalae and Regulates Social Interaction and Memory. Cell Rep 29:34-48.e4 (2019). PubMed: 31577954