Cyclosporin A，PP2B抑制剂(ab120114)
Key features and details
- PP2B inhibitor
- CAS Number: 59865-13-3
- Purity: > 99%
Soluble in DMSO to 100 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Cyclosporin A，PP2B抑制剂 -
描述
PP2B抑制剂 -
纯度
> 99% -
CAS编号
59865-13-3 -
化学结构
性能
-
分子量
1202.63 -
PubChem识别号
5284373 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM and in ethanol to 50 mM
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处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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来源
Synthetic
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研究领域
图片
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Chemical Structure - Cyclosporin A, PP2B inhibitor (ab120114)2D chemical structure image of ab120114, Cyclosporin A, PP2B inhibitor
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (13)
ab120114 被引用在 13 文献中.
- Liao Z et al. The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP. Cells 11:N/A (2022). PubMed: 36078115
- Ding Y et al. Protecting P-glycoprotein at the blood-brain barrier from degradation in an Alzheimer's disease mouse model. Fluids Barriers CNS 18:10 (2021). PubMed: 33676539
- Matsubara (???) Y et al. Inhibition of T-Cells by Cyclosporine A Reduces Macrophage Accumulation to Regulate Venous Adaptive Remodeling and Increase Arteriovenous Fistula Maturation. Arterioscler Thromb Vasc Biol 41:e160-e174 (2021). PubMed: 33472405
- Zhang MJ et al. CD38 triggers inflammasome-mediated pyroptotic cell death in head and neck squamous cell carcinoma. Am J Cancer Res 10:2895-2908 (2020). PubMed: 33042624
- Xie Y et al. Ultrasound Molecular Imaging of Lymphocyte-endothelium Adhesion Cascade in Acute Cellular Rejection of Cardiac Allografts. Transplantation 103:1603-1611 (2019). PubMed: 31343564