Citalopram，5-HT reuptake抑制剂(ab120133)
Key features and details
- 5-HT reuptake inhibitor
- CAS Number: 59729-32-7
- Soluble in water to 10 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Citalopram，5-HT reuptake抑制剂 -
描述
5-HT reuptake抑制剂 -
生物学描述
Selective serotonin reuptake inhibitor. Antidepressant in vivo.
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CAS编号
59729-32-7 -
化学结构
性能
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化学名称
1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile hydrobromide -
分子量
405.30 -
分子式
C20H21FN2O.HBr -
PubChem识别号
77995 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 10 mM and in ethanol to 50 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Br.CN(C)CCCC2(OCc1cc(ccc12)C#N)c3ccc(F)cc3 -
来源
Synthetic
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研究领域
图片
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Chemical Structure - Citalopram, 5-HT reuptake inhibitor (ab120133)2D chemical structure image of ab120133, Citalopram, 5-HT reuptake inhibitor
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (5)
ab120133 被引用在 5 文献中.
- Burke DA & Alvarez VA Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. Cell Rep 39:110795 (2022). PubMed: 35545050
- Collins HM et al. Effect of selective serotonin reuptake inhibitor discontinuation on anxiety-like behaviours in mice. J Psychopharmacol 36:794-805 (2022). PubMed: 35607713
- Unger EK et al. Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning. Cell 183:1986-2002.e26 (2020). PubMed: 33333022
- Podkowa K et al. Antidepressant-like effects of scopolamine in mice are enhanced by the group II mGlu receptor antagonist LY341495. Neuropharmacology 111:169-179 (2016). PubMed: 27569995
- Howerton AR et al. Dorsal raphe neuroinflammation promotes dramatic behavioral stress dysregulation. J Neurosci 34:7113-23 (2014). PubMed: 24849347