cis-ACBD (1-Aminocyclobutane-1,3-dicarboxylic acid),L-glutamate uptake抑制剂
cis-ACBD (1-Aminocyclobutane-1,3-dicarboxylic acid), L-glutamate uptake inhibitor
Be the first to review this product! Submit a review
|
(0 Publication)
MW 159.14 Da. Selective, competitive L-glutamate uptake inhibitor (IC50 = 30 μM). Increases basal and potassium evoked D-aspartate release.
查看别名
15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE, 15 LOX 1, 15 lipoxygenase 1, 15-LOX, ALOX15, AW490526, Arachidonate 15-lipoxygenase, Arachidonate omega-6 lipoxygenase, EB11, EIEE27, EPND, FESD, GRIN 2A, GRIN 2B, GRIN3A, GRIN3B, GluN1, GluN2A, GluN2C, GluN2D, Glutamate Receptor Ionotropic N Methyl D Aspartate 2B, Glutamate Receptor Ionotropic N Methyl D Aspartate 2C, Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B, Glutamate Receptor Ionotropic N methyl D aspartate 3A, Glutamate [NMDA] receptor subunit epsilon-1, Glutamate [NMDA] receptor subunit epsilon-2, Glutamate [NMDA] receptor subunit epsilon-3, Glutamate [NMDA] receptor subunit epsilon-4, Glutamate [NMDA] receptor subunit zeta-1, Glutamate receptor, Glutamate receptor ionotropic, Glutamate receptor ionotropic N methyl D aspartate 1, Glutamate receptor ionotropic N methyl D aspartate 2A, Glutamate receptor ionotropic N methyl D aspartate 3B, Glutamate receptor ionotropic NMDA2B, Glutamate receptor ionotropic, N-methyl-D aspartate, subunit 1, Glutamate receptor ionotropic, NMDA 2C, Glutamate receptor subunit epsilon 2, Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, Glutamate receptor, ionotropic, NMDA2B (epsilon 2), Grin2c, Grin2d, LKS, LOG15, LOX15_HUMAN, MGC142178, MGC142180, MRD6, MRD8, N Methly D Aspartate Receptor Channel Subunit Epsilon 3, N methyl D asparate receptor channel subunit epsilon 2, N methyl D aspartate receptor channel subunit zeta 1, N methyl D aspartate receptor channel, subunit epsilon 1, N methyl D aspartate receptor subunit 2A, N methyl D aspartate receptor subunit 2B, N methyl D aspartate receptor subunit 2C, N methyl d aspartate receptor subunit 2D, N-methyl D-aspartate receptor subtype 2A, N-methyl D-aspartate receptor subtype 2B, N-methyl D-aspartate receptor subtype 2C, N-methyl D-aspartate receptor subtype 2D, N-methyl-D-aspartate receptor, N-methyl-D-aspartate receptor subunit 3, N-methyl-D-aspartate receptor subunit NR1, NMD-R1, NMDA 1, NMDA 2D, NMDA NR2B, NMDA receptor 1, NMDA receptor subtype 2A, NMDA receptor subunit 3A, NMDA receptor subunit 3B, NMDAR, NMDAR2C, NMDAR2D, NMDE1_HUMAN, NMDE2_HUMAN, NMDE3_HUMAN, NMDE4_HUMAN, NMDZ1_HUMAN, NR1, NR2A, NR2B, NR2C, NR2D, NR3, OTTHUMP00000041930, OTTHUMP00000160135, OTTHUMP00000174531, estrogen receptor binding CpG island, glutamate receptor ionotropic NMDA 2D, glutamate receptor ionotropic, NMDA 1, hNR 3, hNR2A
- Chemical Structure
Lab
Chemical Structure - cis-ACBD (1-Aminocyclobutane-1,3-dicarboxylic acid), L-glutamate uptake inhibitor (AB146128)
2D chemical structure image of ab146128, cis-ACBD (1-Aminocyclobutane-1,3-dicarboxylic acid), L-glutamate uptake inhibitor
性能和储存信息
运输条件
推荐的短期储存条件
推荐的长期储存条件
储存信息
补充信息
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
NMDA receptors function as part of a larger receptor complex on the cell membrane playing a critical role in learning and memory. They act by permitting the flow of calcium ions into the neuron when activated by the neurotransmitter glutamate in conjunction with membrane depolarization. This ion influx triggers downstream signaling pathways that lead to long-term potentiation (LTP) a mechanism for synaptic strengthening.
Pathways
NMDA receptors are essential components of the glutamatergic signaling pathway. They participate in the calcium/calmodulin-dependent protein kinase (CaMK) pathway and interact with other proteins such as PSD-95 which organizes receptor complexes in the synapse. The pathways coordinate to modulate synaptic plasticity important for processes like neuronal development and adult neurogenesis.
Abcam Product Promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com