Cilostamide,PDE3抑制剂(ab141273)
Key features and details
- Potent, selective PDE3 inhibitor
- CAS Number: 68550-75-4
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Cilostamide,PDE3抑制剂 -
描述
Potent,selective PDE3抑制剂 -
生物学描述
Potent, selective PDE3 inhibitor (IC50 values are 27 and 50 nM for PDE3A and PDE3B, respectively). Inhibits ADP-induced platelet aggregation (IC50 = 16.8 μM). Antithrombotic effects in vivo. Orally active.
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纯度
> 98% -
CAS编号
68550-75-4 -
化学结构
性能
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化学名称
N-Cyclohexyl-4-[(1,2-dihydro-2-oxo-6-quinolinyl)oxy]-N-methylbutanamide -
分子量
342.44 -
分子式
C20H26N2O3 -
PubChem识别号
2753 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN(C1CCCCC1)C(=O)CCCOc2ccc3NC(=O)C=Cc3c2 -
来源
Synthetic
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (1)
ab141273 被引用在 1 文献中.
- Jönsson C et al. Insulin and ß-adrenergic receptors mediate lipolytic and anti-lipolytic signalling that is not altered by type 2 diabetes in human adipocytes. Biochem J 476:2883-2908 (2019). PubMed: 31519735