CGP 39551，competitive NMDA拮抗剂(ab120128)
Key features and details
- Competitive NMDA antagonist
- CAS Number: 127910-32-1
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
CGP 39551，competitive NMDA拮抗剂 -
描述
Competitive NMDA拮抗剂 -
生物学描述
Competitive NMDA receptor antagonist (Ki = 310 nM for displacement of CPP binding in rat brain). Potent oral anticonvulsant activity in vivo.
Also available in simple stock solutions (ab146683) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS编号
127910-32-1 -
化学结构
性能
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化学名称
(E)-4-(Ethoxycarbonyl)-4-amino-2-methylbut-2-enylphosphonic acid -
分子量
237.19 -
分子式
C8H16NO5P -
PubChem识别号
6372334 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C/C(=CC(N)C(=O)OCC)CP(=O)(O)O -
来源
Synthetic
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研究领域
图片
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Chemical Structure - CGP 39551, competitive NMDA antagonist (ab120128)2D chemical structure image of ab120128, CGP 39551, competitive NMDA antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (1)
ab120128 被引用在 1 文献中.
- Grauert A et al. Endogenous zinc depresses GABAergic transmission via T-type Ca(2+) channels and broadens the time window for integration of glutamatergic inputs in dentate granule cells. J Physiol 592:67-86 (2014). PubMed: 24081159