CGP 37849，competitive NMDA拮抗剂(ab120127)
Key features and details
- Competitive NMDA antagonist
- CAS Number: 127910-31-0
- Soluble in water to 100 mM (with warming)
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
CGP 37849，competitive NMDA拮抗剂 -
描述
Competitive NMDA拮抗剂 -
生物学描述
Competitive NMDA receptor antagonist (Ki = 35 nM for displacement of CPP binding in rat brain). Potent oral anticonvulsant activity in vivo.
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CAS编号
127910-31-0 -
化学结构
性能
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化学名称
(E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid -
分子量
209.14 -
分子式
C6H12NO5P -
PubChem识别号
5950212 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM (with warming) -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C/C(=CC(N)C(=O)O)CP(=O)(O)O -
来源
Synthetic
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (2)
ab120127 被引用在 2 文献中.
- Du H et al. Neuregulin-1 impairs the long-term depression of hippocampal inhibitory synapses by facilitating the degradation of endocannabinoid 2-AG. J Neurosci 33:15022-31 (2013). PubMed: 24048832
- Homma R et al. In vivo functional properties of juxtaglomerular neurons in the mouse olfactory bulb. Front Neural Circuits 7:23 (2013). PubMed: 23459031