CGP 35348，GABAB拮抗剂(ab120167)
Key features and details
- GABAB antagonist, brain penetrant
- CAS Number: 123690-79-9
Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
CGP 35348，GABAB拮抗剂 -
描述
GABAB拮抗剂，brain penetrant -
生物学描述
Selective GABAB antagonist (IC50 = 34 μM). Brain penetrant in vivo.
Also available in simple stock solutions (ab146707) - add 1 ml of water to get an exact, ready-to-use concentration. -
CAS编号
123690-79-9 -
化学结构
性能
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化学名称
(3-Aminopropyl)(diethoxymethyl)phosphinic acid
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分子量
225.22 -
分子式
C8H20NO4P -
PubChem识别号
107699 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM
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处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCOC(OCC)P(=O)(O)CCCN -
来源
Synthetic
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研究领域
图片
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Chemical Structure - CGP 35348, GABAB antagonist (ab120167)2D chemical structure image of ab120167, CGP 35348, GABAB antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (1)
ab120167 被引用在 1 文献中.
- Ma J & Leung LS GABA(B) receptor blockade in the hippocampus affects sensory and sensorimotor gating in Long-Evans rats. Psychopharmacology (Berl) 217:167-76 (2011). PubMed: 21484240