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AB120167

CGP 35348, GABAB antagonist

CGP 35348, GABAB antagonist

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(2 Publications)

MW 225.22 Da. Selective GABAB antagonist (IC50 = 34 μM). Brain penetrant *in vivo*. Also available in simple stock solutions (ab146707) - add 1 ml of water to get an exact, ready-to-use concentration.

查看别名

BcDNA:GH07312, CG6706, CT20836, D Gaba2, FLJ36928, FLJ92613, G-protein coupled receptor 51, GAB B R2, GABA-B receptor 1, GABA-B receptor 2, GABA-B-R1, GABA-B-R2, GABAB subunit 1c, GABBR1, GABBR1 3, GABR1_HUMAN, GABR2_HUMAN, GH07312, GPR 51, GPRC 3B, GPRC3A, Gamma aminobutyric acid (GABA) B receptor 1, Gamma aminobutyric acid B receptor 2, Gamma aminobutyric acid GABA B receptor 2, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, Gb 2, Gb1, HG 20, HRIHFB2099, Metabotropic GABA B receptor subtype 2, OTTHUMP00000021776, OTTHUMP00000063797, R2 SUBUNIT, Seven transmembrane helix receptor, dJ271M21.1.1, dJ271M21.1.2

1 Images
Chemical Structure - CGP 35348, GABAB antagonist (AB120167)
  • Chemical Structure

Lab

Chemical Structure - CGP 35348, GABAB antagonist (AB120167)

2D chemical structure image of ab120167, CGP 35348, GABAB antagonist

关键信息

CAS 号

123690-79-9

形式

Solid

form

分子量

225.22 Da

分子式

C<sub>8</sub>H<sub>2</sub><sub>0</sub>NO<sub>4</sub>P

PubChem

107699

属性

Synthetic

溶解度

Soluble in water to 100 mM

生化试剂名称

3-Aminopropyl(diethoxymethyl)phosphinic acid

生物学描述

Selective GABAB antagonist (IC50 = 34 μM). Brain penetrant *in vivo*. Also available in simple stock solutions (ab146707) - add 1 ml of water to get an exact, ready-to-use concentration.

经典 SMILES

CCOC(OCC)P(=O)(CCCN)O

InChi

InChI=1S/C8H20NO4P/c1-3-12-8(13-4-2)14(10,11)7-5-6-9/h8H,3-7,9H2,1-2H3,(H,10,11)

InChiKey

QIIVUOWTHWIXFO-UHFFFAOYSA-N

IUPAC 名

3-aminopropyl(diethoxymethyl)phosphinic acid

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性能和储存信息

运输条件
Ambient - Can Ship with Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
储存信息
Store under desiccating conditions|The product can be stored for up to 12 months
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产品实验方案

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Reproductive medicine and biology 22:e12528 PubMed37476368

2023

Gamma-aminobutyric acid (GABA) can affect physiological processes in preimplantation embryos via GABA and GABA receptors.

Applications

Unspecified application

Species

Unspecified reactive species

Veronika Kovaříková,Alexandra Špirková,Zuzana Šefčíková,Jozef Pisko,Laura Kalatová,Juraj Koppel,Dušan Fabian,Štefan Čikoš

Psychopharmacology 217:167-76 PubMed21484240

2011

GABA(B) receptor blockade in the hippocampus affects sensory and sensorimotor gating in Long-Evans rats.

Applications

Unspecified application

Species

Unspecified reactive species

Jingyi Ma,L Stan Leung
View all publications
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Primary Antibodies

AB238130

Anti-GABA B Receptor 1 antibody [EPR22954-47]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GABA B Receptor 1 antibody [EPR22954-47] (AB238130)

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