Bromocriptine mesylate，D2-like dopamine receptor激动剂(ab120574)
Key features and details
- Potent, selective D2-like dopamine receptor agonist
- CAS Number: 22260-51-1
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 25 mM (with heating)
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Bromocriptine mesylate，D2-like dopamine receptor激动剂 -
描述
Potent，selective D2-like dopamine receptor激动剂 -
生物学描述
Potent, selective D2-like dopamine receptor agonist (Ki values are ~8 (D2), ~5 (D3), ~290 (D4), ~440 (D1) and ~450 nM (D5)). Inhibits the release of pituitary prolactin and stimulates motor activity in Parkinson's disease. Also reverses glutamate transporter 1 (GLT-1) activity, increasing glutamate levels.
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纯度
> 99% -
CAS编号
22260-51-1 -
化学结构
性能
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化学名称
(5a)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione methanesulfonate -
分子量
750.70 -
分子式
C32H40BrN5O5.CH3SO3H -
PubChem识别号
31100 -
存放说明
Store at +4°C. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM and in ethanol to 25 mM (with heating) -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CS(=O)(=O)O.Brc3nc2cccc1C4=C[C@H](CN(C)[C@@H]4Cc3c12)C(=O)N[C@@]7(O[C@]6(O)N([C@@H](CC(C)C)C(=O)N5CCC[C@H]56)C7=O)C(C)C -
来源
Synthetic
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研究领域
图片
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Chemical Structure - Bromocriptine mesylate, D2-like dopamine receptor agonist (ab120574)2D chemical structure image of ab120574, Bromocriptine mesylate, D2-like dopamine receptor agonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (1)
ab120574 被引用在 1 文献中.
- Ji M et al. An Antiviral Peptide from Alopecosa nagpag Spider Targets NS2B-NS3 Protease of Flaviviruses. Toxins (Basel) 11:N/A (2019). PubMed: 31658707