BIIB 021 (ab273599)
Key features and details
- Selective, competitive HSP90 inhibitor.
- CAS Number: 848695-25-0
- Purity: > 98%
Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
BIIB 021 -
描述
Selective，competitive HSP90抑制剂. -
生物学描述
Selective, Hsp90 competitive inhibitor (Ki = 1.7 nM). Displays no significant activity at a range of ATP-binding kinases or Na+K+ ATPase. Induces degradation of HER-2 in vitro (EC50 = 38 nM in MCF-7 cells). Inhibits growth and promotes cell death in a variety of human tumor cells. Orally bioavailable.
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纯度
> 98% -
CAS编号
848695-25-0 -
化学结构
性能
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化学名称
6-Chloro-9-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-9H-purin-2-amine
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分子量
318.80 -
分子式
C14H15ClN6O -
PubChem识别号
16736529 -
存放说明
Shipped at room temperature. Store at -20°C. -
溶解度概述
Soluble in DMSO to 100 mM
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处理
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CN=C(C(=C1OC)C)CN2C=NC3=C2N=C(N=C3Cl)N -
来源
Synthetic
图片
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Chemical Structure - BIIB 021 (ab273599)
Chemical structure of BIIB 021, 848695-25-0
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab273599 尚未被引用在任何文献中。