AZD1152-HQPA,Aurora B kinase抑制剂
AZD1152-HQPA, Aurora B kinase inhibitor
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(1 Publication)
AZD1152-HQPA (CAS No: 722544-51-6)(ab142049). Potent, selective Aurora B kinase inhibitor (IC50 = 0.37 nM). Induces apoptosis in vitro. Antitumor agent. Cell-permeable. Active in vitro and in vivo MW 507.6. Purity >99%.
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Alpha-PAK, Beta PAK, CAM kinase II delta, CAMK 2, CAMK 2B, CAMK 2d, CAMK2G, CAMKA, CDC2L1, CDK11, CDKN1A, CaM kinase II, CaM kinase II alpha, CaM kinase II beta, CaM kinase II gamma, CaM kinase II subunit alpha, CaMK-II subunit alpha, Calcium / calmodulin dependent protein kinase II delta, Calcium/calmodulin dependent protein kinase II gamma, Calcium/calmodulin-dependent protein kinase II-alpha, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Camk2a, Cell division cycle 2-like protein kinase 1, Cell division protein kinase 11B, EC 2.7.11.1, EC=2.7.11.22, GSD9C, Galactosyltransferase-associated protein kinase p58/GTA, Gamma-PAK, Germinal center kinase like kinase, Germinal center kinase-related protein kinase, ITSLRE serine/threonine protein kinase CDC2L1, KCC2A_HUMAN, KHS, Kinase homologous to SPS1/STE20, MAP4K3, MAPK/ERK kinase kinase kinase 3, MAPK/ERK kinase kinase kinase 5, MAPKKKK3, MEK kinase kinase 3, MEK kinase kinase 5, MEKKK 3, MEKKK 5, MRX30, MRX47, OPHN3, Oligophrenin 3, P21 (CDKN1A) activated kinase 2, P21 (CDKN1A) activated kinase 3, P21 protein (Cdc42/Rac) activated kinase 1, P21 protein (Cdc42/Rac) activated kinase 3, P21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related), P58, PAK alpha, PAK3beta, PAK65, PAKgamma, PHK gamma LT, PHK gamma T, PITSLREA, PK58, PSK C3, Phosphorylase b kinase gamma catalytic chain testis/liver isoform, Phosphorylase b kinase gamma catalytic chain, liver/testis isoform, Phosphorylase kinase catalytic subunit gamma 2, Phosphorylase kinase gamma subunit 2, Phosphorylase kinase subunit gamma 2, Phosphorylase kinase, gamma 2 (testis), Phosphorylase kinase, gamma 2 (testis/liver), RAB8IPL1, S6/H4 kinase, STE20 homolog, yeast, Serine/threonine protein kinase PAK 2, Serine/threonine protein kinase PAK 3, Serine/threonine protein kinase PHKG2, Serine/threonine-protein kinase PAK 1, TUBA1, TUBA1A, TUBA2, TUBA3, TUBA3C, TUBA4A, Tubulin, alpha 1a, Tubulin, alpha 3c, Tubulin, alpha 4a, bPAK, calcium/calmodulin-dependent protein kinase II beta, hPAK3, mitogen-activated protein kinase kinase kinase kinase 3, p21 activated kinase 3, p21 protein (Cdc42/Rac)-activated kinase 2, p21-activated kinase 1, p21-activated kinase 2, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast), p58 CLK 1, p65-PAK
- Chemical Structure
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Chemical Structure - AZD1152-HQPA, Aurora B kinase inhibitor (AB142049)
2D chemical structure image of ab142049, AZD1152-HQPA, Aurora B kinase inhibitor
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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
文献 (1)
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Cell division 15:11 PubMed32973917
2020
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