AZ-20 (ab273623)
Key features and details
- Potent and selective ATR inhibitor
- CAS Number: 1233339-22-4
Soluble in DMSO (up to 20 mg/ml). Solutions in DMSO may be stored at -20°C for up to 1 month.
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
AZ-20 -
描述
Potent and selective ATR抑制剂 -
生物学描述
Potent and selective ATR kinase inhibitor (IC50 = 5 nM in vitro; IC50 = 50 nM in carcinoma cell lines). Selective versus mTOR (8-fold). Displayed selectivity versus a panel of 442 kinases.Inhibits LoVo colorectal adenocarcinoma tumor cell growth.
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纯度
98% -
常规说明
Solutions in DMSO may be stored at -20° for up to 1 month.
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CAS编号
1233339-22-4 -
化学结构
性能
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化学名称
4-[4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl]-1H-indole
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分子量
412.51 -
PubChem识别号
46244454 -
存放说明
Shipped at Room Temperature. Store at -20°C. Store under desiccating conditions. -
溶解度概述
Soluble in DMSO (up to 20 mg/ml). Solutions in DMSO may be stored at -20°C for up to 1 month.
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处理
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@@H]1COCCN1C2=NC(=NC(=C2)C3(CC3)S(=O)(=O)C)C4=C5C=CNC5=CC=C4 -
来源
Synthetic
图片
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Chemical Structure - AZ-20 (ab273623)
Chemical structure of AZ-20, 1233339-22-4
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab273623 尚未被引用在任何文献中。