AS601245,JNK抑制剂(ab145194)
Key features and details
- Potent, selective, ATP competitive JNK inhibitor. Cell-permeable.
- CAS Number: 345987-15-7
- Purity: > 95%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
AS601245,JNK抑制剂 -
描述
Potent,selective,ATP competitive JNK抑制剂. Cell-permeable. -
纯度
> 95% -
CAS编号
345987-15-7 -
化学结构
性能
-
化学名称
(2Z)-2-(3H-1,3-Benzothiazol-2-ylidene)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile -
分子量
372.45 -
分子式
C20H16N6S -
PubChem识别号
11422035 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 25 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C1=CC=C2C(=C1)N/C(=C(/C#N)\C3=NC(=NC=C3)NCCC4=CN=CC=C4)/S2 -
来源
Synthetic
-
研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab145194 被引用在 1 文献中.
- Ivshina MP et al. CPEB1 regulates the inflammatory immune response, phagocytosis, and alternative polyadenylation in microglia. Glia 70:1850-1863 (2022). PubMed: 35635122