AS-041164，PI3K gamma抑制剂(ab120898)
Key features and details
- Potent and selective PI3Kγ inhibitor
- CAS Number: 6318-41-8
- Purity: > 98%
Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
AS-041164，PI3K gamma抑制剂 -
描述
Potent and selective PI3Kγ抑制剂 -
生物学描述
Potent PI3K inhibitor with selectivity for PI3Kγ (IC50 = 70 nM), compared to PI3Kα, β and δ (IC50 values are 240 nM, 1.45 and 1.70 μM, respectively). Shows little or no activity against 38 other common kinases. Blocks neutrophil migration. Active in vivo. -
纯度
> 98% -
CAS编号
6318-41-8 -
化学结构
性能
-
化学名称
5-[(1,3-Benzodioxol-5-yl)methylene]-2,4-thiazolidinedione
-
分子量
249.24 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM
-
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
O=C(/C(S1)=C/C2=CC=C3C(OCO3)=C2)NC1=O -
来源
Synthetic
-
研究领域
图片
-
Chemical Structure - AS-041164, PI3K gamma inhibitor (ab120898)2D chemical structure image of ab120898, AS-041164, PI3K gamma inhibitor
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab120898 尚未被引用在任何文献中。