AF-DX 116 (Otenzepad)，M2拮抗剂(ab120152)
Key features and details
- M2 antagonist
- CAS Number: 102394-31-0
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
AF-DX 116 (Otenzepad)，M2拮抗剂 -
描述
M2拮抗剂 -
别名
- Otenzepad
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生物学描述
Selective M2 receptor antagonist.
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CAS编号
102394-31-0 -
化学结构
性能
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化学名称
11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one -
分子量
421.54 -
分子式
C24H31N5O2 -
PubChem识别号
107867 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 25 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(CN1CCCCC1CN(CC)CC)N4c2ccccc2C(=O)Nc3cccnc34 -
来源
Synthetic
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研究领域
图片
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Chemical Structure - AF-DX 116 (Otenzepad), M2 antagonist (ab120152)2D chemical structure image of ab120152, AF-DX 116 (Otenzepad), M2 antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (3)
ab120152 被引用在 3 文献中.
- Tryon SC et al. Differential Regulation of Prelimbic and Thalamic Transmission to the Basolateral Amygdala by Acetylcholine Receptors. J Neurosci 43:722-735 (2023). PubMed: 36535767
- Choisy SC et al. Acute desensitization of acetylcholine and endothelin-1 activated inward rectifier K(+) current in myocytes from the cardiac atrioventricular node. Biochem Biophys Res Commun 423:496-502 (2012). PubMed: 22683635
- Gorini C et al. Endogenous inhibition of the trigeminally evoked neurotransmission to cardiac vagal neurons by muscarinic acetylcholine receptors. J Neurophysiol 104:1841-8 (2010). PubMed: 20719927