AACOCF3 (Arachidonyl trifluoromethyl ketone)，Phospholipase-A2抑制剂(ab120350)
Key features and details
- Phospholipase-A2 inhibitor
- CAS Number: 149301-79-1
- Purity: >= 98%
Supplied in ethanol (10 mg/ml)
- Form / State: Liquid
- Source: Synthetic
概述
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产品名称
AACOCF3 (Arachidonyl trifluoromethyl ketone)，Phospholipase-A2抑制剂 -
描述
Phospholipase-A2抑制剂 -
别名
- Arachidonyl trifluoromethyl ketone
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生物学描述
Cell-permeable analog of arachidonic acid (ab120916). Widely used as an inhibitor of the 85-kDa cytosolic group IV phospholipase A2 (cPLA2) and calcium-independent group VI phospholipase A2 (iPLA2) (IC50 values are 1.5 and 6.0 μM, respectively) . In non-neural cells, also inhibits cyclooxygenase and acyltransferase activities.
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纯度
>= 98% -
CAS编号
149301-79-1 -
化学结构
性能
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化学名称
(6Z,9Z,12Z,15Z)-1,1,1-Trifluorohenicosa-6,9,12,15-tetraen-2-one
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分子量
356.47 -
PubChem识别号
5280436 -
存放说明
Store at -20°C. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Supplied in ethanol (10 mg/ml)
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处理
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
FC(F)(F)C(=O)CCCC=C/C/C=CC/C=CC/C=CCCCCC -
来源
Synthetic
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研究领域
图片
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Chemical Structure - AACOCF3 (Arachidonyl trifluoromethyl ketone), Phospholipase-A2 inhibitor (ab120350)2D chemical structure image of ab120350, AACOCF3 (Arachidonyl trifluoromethyl ketone), Phospholipase-A2 inhibitor
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab120350 被引用在 1 文献中.
- Monson EA et al. Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response. Nat Commun 12:4303 (2021). PubMed: 34262037