2,3-Butanedione 2-monoxime (BDM)，Non-selective myosin ATPase抑制剂(ab120616)
Key features and details
- Non-selective myosin ATPase inhibitor
- CAS Number: 57-71-6
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
2,3-Butanedione 2-monoxime (BDM)，Non-selective myosin ATPase抑制剂 -
描述
Non-selective myosin ATPase抑制剂 -
别名
- BDM
- Biacetyl monoxime
- Diacetyl monoxime
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生物学描述
Non-selective myosin ATPase inhibitor (Ki = 5 mM at myosin II). Potent Kv2.1 (DRK1) and L-Type Ca2+ channel inhibitor (Ki and IC50 values are 10.7 nM and 5.8 mM, respectively). Blood-brain barrier permeable. Inhibits muscle contraction.
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CAS编号
57-71-6 -
化学结构
性能
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化学名称
2,3-Butanedione monoxime -
分子量
101.10 -
分子式
C4H7NO2 -
存放说明
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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来源
Synthetic
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研究领域
图片
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Chemical Structure - 2,3-Butanedione 2-monoxime (BDM), Non-selective myosin ATPase inhibitor (ab120616)2D chemical structure image of ab120616, 2,3-Butanedione 2-monoxime (BDM), Non-selective myosin ATPase inhibitor
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (3)
ab120616 被引用在 3 文献中.
- Cornean A et al. Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction. Elife 11:N/A (2022). PubMed: 35373735
- Li Q et al. KV4 channels in isolectin B4 muscle dorsal root ganglion neurons of rats with experimental peripheral artery disease: effects of bradykinin B1 and B2 receptors. Am J Physiol Regul Integr Comp Physiol 323:R616-R627 (2022). PubMed: 36094447
- Gerbin KA et al. Cell states beyond transcriptomics: Integrating structural organization and gene expression in hiPSC-derived cardiomyocytes. Cell Syst 12:670-687.e10 (2021). PubMed: 34043964