(-)-MK 801 maleate，Non competitive NMDA拮抗剂(ab120028)
Key features and details
- Non competitive NMDA antagonist; less active enantiomer
- CAS Number: 77086-19-2
- Soluble in water to 25 mM, in DMSO to 100 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
(-)-MK 801 maleate，Non competitive NMDA拮抗剂 -
描述
Non competitive NMDA拮抗剂; less active enantiomer -
生物学描述
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CAS编号
77086-19-2 -
化学结构
性能
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化学名称
(5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate -
分子量
337.37 -
分子式
C16H15N.C4H4O4 -
PubChem识别号
16219612 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 25 mM, in DMSO to 100 mM and in ethanol to 50 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(O)/C=CC(=O)O.C[C@]42N[C@@H](Cc1ccccc12)c3ccccc34 -
来源
Synthetic
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研究领域
相关产品
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Related Products
图片
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Chemical Structure - (-)-MK 801 maleate, Non competitive NMDA antagonist (ab120028)2D chemical structure image of ab120028, (-)-MK 801 maleate, Non competitive NMDA antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (2)
ab120028 被引用在 2 文献中.
- Gallego-Delgado P et al. Neuroinflammation in the normal-appearing white matter (NAWM) of the multiple sclerosis brain causes abnormalities at the nodes of Ranvier. PLoS Biol 18:e3001008 (2020). PubMed: 33315860
- Fijal K et al. Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats. Psychopharmacology (Berl) 231:269-81 (2014). PubMed: 23954911
