(-)-Cytisine，neuronal nicotinic激动剂(ab120537)
Key features and details
- Potent, selective nAChR agonist
- CAS Number: 485-35-8
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
(-)-Cytisine，neuronal nicotinic激动剂 -
描述
Potent，selective nAChR激动剂 -
生物学描述
Potent, selective agonist at neuronal nicotinic receptors. Acts as a partial agonist at β2-containing nicotinic receptors. (Ki values are 2 (α4β2), 5890 (α7), 480 (α3β4), 329 (α6/α4β4) and 492 nM (α1β1γδ)).
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CAS编号
485-35-8 -
化学结构
性能
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化学名称
(1R,5S)-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one -
分子量
190.24 -
分子式
C11H14N2O -
PubChem识别号
22407 -
存放说明
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C2C=CC=C3C1CC(CNC1)CN23 -
来源
Synthetic
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研究领域
图片
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Chemical Structure - (-)-Cytisine, neuronal nicotinic agonist (ab120537)2D chemical structure image of ab120537, (-)-Cytisine, neuronal nicotinic agonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (1)
ab120537 被引用在 1 文献中.
- Luo R et al. Direct and GABA-mediated indirect effects of nicotinic ACh receptor agonists on striatal neurones. J Physiol 591:203-17 (2013). PubMed: 23045343