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AB115091

Histone H3 Total Quantification试剂盒(Colorimetric)

Histone H3 Total Quantification Kit (Colorimetric)

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(2 Publications)

Histone H3 Total Quantification Kit (Colorimetric) (ab115091) enables the user to quantify levels of histone H3 proteins independent of their modified states.

查看别名

H3FA, HIST1H3A, H3C2, H3FL, HIST1H3B, H3C3, H3FC HIST1H3C, H3C4, H3FB, HIST1H3D, H3C6, H3FD, HIST1H3E, H3C7, H3FI, HIST1H3F, H3C8, H3FH, HIST1H3G, H3C10, H3FK, HIST1H3H, H3C11, H3FF, HIST1H3I, H3C12, H3FJ, HIST1H3J, HIST1H3C, H3FC, H3C1, Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l

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Functional Studies - Histone H3 Total Quantification Kit (Colorimetric) (AB115091)
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Supplier Data

Functional Studies - Histone H3 Total Quantification Kit (Colorimetric) (AB115091)

Measurement of histone H3 with different concentrations of the included H3 standard in theHistone H3 Total Quantification Kit (Colorimetric) (ab115091).

关键信息

检测方法

Colorimetric

样品类型

Tissue, Suspension cells, Adherent cells

反应种属

Mouse, Rat, Human

灵敏度

= 10 ng/well

范围

20 - 1000 ng/well

检测时间

2h 30m

检测平台

Microplate reader

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搭配使用产品

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AB233486

Global DNA Methylation Assay Kit (5 Methyl Cytosine, Colorimetric)

Functional Studies - Global DNA Methylation Assay Kit (5 Methyl Cytosine, Colorimetric) (AB233486)

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AB115072

Histone H3 (tri-methyl K27) Quantification Kit (Colorimetric)

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Assay Kits

AB115127

Histone H3 (phospho S10) Assay Kit (Colorimetric)

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Sample Prep & Detection Kits

AB113476

Histone Extraction Kit

Functional Studies - Histone Extraction Kit (AB113476)

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产品详情

Histone H3 Total Quantification Kit (Colorimetric) (ab115091) enables the user to quantify levels of histone H3 proteins independent of their modified states. It can also be used for normalizing the modified histone H3 content of samples when run in parallel with Abcam's histone modification quantification kit series. ab115091 is suitable for specifically measuring total histone H3 on mammalian samples such as human, mouse, and rat, including fresh and frozen tissues and cultured adherent and suspension cells.

Histone H3 can undergo several epigenetic modifications that influence cellular processes such as transcription activation/inactivation, chromosome packaging, and DNA damage/repair. These modifications including acetylation, phosphorylation or methylation occur on the N-terminal tail domains of histone H3 through a variety of histone modifying enzymes. In most species, histone H3 is primarily acetylated at K9, K14, K18, K23 and K56, methylated at K4, K9, K27, K36 and K79, and phosphorylated at S10, S28, T3 and T11, respectively.

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规格

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性能和储存信息

运输条件
Blue Ice
推荐的短期储存条件
Multi
推荐的长期储存条件
Multi
储存信息
Please refer to protocols
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产品实验方案

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靶点信息

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
See full target information H3C1
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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Sensors & diagnostics 4:416-424 PubMed40162346

2025

Lateral flow assay-based detection of nuclear fusion oncoprotein: implications for screening of acute promyelocytic leukemia.

Applications

Unspecified application

Species

Unspecified reactive species

Maede Chabi,Binh Vu,Kristen Brosamer,Sophia Song,Vijay Maranholkar,Zihua Zeng,Youli Zu,Rashmi Kanagal-Shamanna,Jacinta C Conrad,Richard C Willson,Katerina Kourentzi

Translational medicine of aging 4:22-31 PubMed32462102

2020

Remodeling of the H3 nucleosomal landscape during mouse aging.

Applications

Unspecified application

Species

Unspecified reactive species

Yilin Chen,Juan I Bravo,Jyung Mean Son,Changhan Lee,Bérénice A Benayoun
View all publications
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