DNA-Protein Binding Assay试剂盒(Colorimetric) (ab117139)
Key features and details
- Detection method: Colorimetric
- Platform: Microplate reader
- Assay time: 3 hr
概述
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产品名称
DNA-Protein Binding Assay试剂盒(Colorimetric)
参阅全部 DNA-protein 试剂盒 -
检测方法
Colorimetric -
检测时间
3h 00m -
种属反应性
与反应: Mouse, Human
预测可用于: Mammals
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产品概述
Protein-DNA interactions play a critical role for cellular functions such as signal transduction, gene transcription and epigenetic silencing. Identifying the genetic targets of DNA binding proteins and knowing the mechanishm of protein-DNA interaction is important for understanding cellular processes.
DNA-Protein Binding Assay Kit (Colorimetric) (ab117139) allows the user to investigate direct in vitro protein-DNA interaction, using dsDNA of choice, within 3 hours. ab117139 is specifically suitable for detection of transcription factor activation in mammalian tissue and cell extracts.
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平台
Microplate reader
性能
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存放说明
Store at +4°C. Please refer to protocols. -
组件 96 tests 10X Wash Buffer 1 x 20ml 8 Well Assay Strips (with Frame) 12 units Antibody Dilution Buffer 1 x 20ml Assay Binding Buffer 1 x 4ml Developing Solution 1 x 10ml Stop Solution 1 x 6ml -
研究领域
数据表及文件
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SDS download
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Datasheet download
文献 (8)
ab117139 被引用在 8 文献中.
- Kavitha B et al. Molecular characterization and re-interpretation of HNF1A variants identified in Indian MODY subjects towards precision medicine. Front Endocrinol (Lausanne) 14:1177268 (2023). PubMed: 37396188
- Lee S et al. Phenotypic and molecular basis of SIX1 variants linked to non-syndromic deafness and atypical branchio-otic syndrome in South Korea. Sci Rep 13:11776 (2023). PubMed: 37479820
- Shrestha R et al. The Histone Methyltransferase Gene G9A Is Regulated by Nuclear Receptor 4A1 in Alveolar Rhabdomyosarcoma Cells. Mol Cancer Ther 20:612-622 (2021). PubMed: 33277444
- Kim H et al. Loss-of-function of ARABIDOPSIS F-BOX PROTEIN HYPERSENSITIVE TO ABA 1 enhances drought tolerance and delays germination. Physiol Plant 173:2376-2389 (2021). PubMed: 34687457
- Blanco-Cantó ME et al. Novel EGR2 variant that associates with Charcot-Marie-Tooth disease when combined with lipopolysaccharide-induced TNF-a factor T49M polymorphism. Neurol Genet 6:e407 (2020). PubMed: 32337334
- Kwon HK et al. FoxP3 scanning mutagenesis reveals functional variegation and mild mutations with atypical autoimmune phenotypes. Proc Natl Acad Sci U S A 115:E253-E262 (2018). PubMed: 29269391
- Kwon HK et al. Different molecular complexes that mediate transcriptional induction and repression by FoxP3. Nat Immunol 18:1238-1248 (2017). PubMed: 28892470
- Lee YL et al. MAF1 represses CDKN1A through a Pol III-dependent mechanism. Elife 4:e06283 (2015). Functional Studies . PubMed: 26067234