AB197441

人Cytokine抗体阵列D (40 Targets) - Quantitative

Name: 人Cytokine抗体阵列D (40 Targets) - Quantitative (ab197441)| Abcam中文官网
Brand: Abcam Limited
SKU: AB197441
Price: 33596 CNY
Availability: InStock

Human Cytokine Antibody Array D (40 Targets) - Quantitative

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ab197441 can be used for quantitative measurement of 40 Human cytokines.

查看别名

UNQ868/PRO1885, ACE2, Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, Angiotensin-converting enzyme-related carboxypeptidase, Metalloprotease MPROT15, ACEH, ACE-related carboxypeptidase

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Multiplex Protein Detection - Human Cytokine Antibody Array D (40 Targets) - Quantitative (AB197441)

Multiplex Protein Detection

Supplier Data

Multiplex Protein Detection - Human Cytokine Antibody Array D (40 Targets) - Quantitative (AB197441)

Standard Curve obtained using Abcam Human Cytokine Antibody Array D (40 Targets) - Quantitative (ab197441).

Multiplex Protein Detection

Supplier Data

Multiplex Protein Detection - Human Cytokine Antibody Array D (40 Targets) - Quantitative (AB197441)

Array map for Abcam Human Cytokine Antibody Array D (40 Targets) - Quantitative (ab197441).

Multiplex Protein Detection

Supplier Data

Multiplex Protein Detection - Human Cytokine Antibody Array D (40 Targets) - Quantitative (AB197441)

Assay summary for Abcam Human Cytokine Antibody Array D (40 Targets) - Quantitative (ab197441).

关键信息

检测类型

Quantitative

反应种属

Human

靶标

ACE2

target

检测方法

Fluorescent

检测平台

Multiplex

样品类型

Tissue Lysate, Plasma, Cell culture media, Serum, Other biological fluids, Cell Lysate

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产品详情

ab197441 can be used for quantitative measurement of 40 Human cytokines. Suitable for serum, plasma, cell culture media, other body fluids, cell and tissue lysates.
Targets names: ACE-2, Albumin, AMICA, ANG-4, BAFF, CA19-9, CD163, Clusterin, CRTAM, CXCL14, Cystatin C, Decorin , Dkk-3, DLL1, Fetuin A, aFGF, FOLR1, Furin, GASP-1, GASP-2, GCSF R, HAI-2, IL-17B R, IL-27, LAG-3 , LDL R, Pepsinogen I, RANK, RBP4, SOST, Syndecan-1, TACI, TFPI, TSP-1, TRAIL R2, TRANCE, Troponin I, uPA, VE-Cadherin, WISP-1.

Quantitative antibody arrays can be used to quantitate up to 40 cytokines with as little as 50 µL of sample. Arrays are available for 400 human and 200 mouse proteins. Each glass slide is spotted with 16 identical antibody arrays and is provided with a 16 well gasket to allow separate samples to be applied to each array. Each antibody is spotted in quadruplicate in each array. For reproducible quantitation, eight of the arrays are used with a cocktail of protein standards to produce a standard curve. The same 8 standard curve arrays can be used across multiple slides, allowing measurement of 22 experimental samples with 2 slides, 36 with 3 slides etc. For high through-put, 4 slides can be nested into a tray matching a standard microplate, allowing automated processing with a liquid handling workstation. Array processing can be completed within one working day (see workflow diagram below) and arrays can be analyzed with a wide number of laser glass slide array / gene microarray scanners. If you don’t have a suitable scanner then we recommend our membrane antibody arrays, which can be analyzed with any WB chemiluminescent reader. The standard is affinity purified. "

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规格

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性能和储存信息

运输条件

Blue Ice

储存信息

-20°C

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产品实验方案

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靶点信息

Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis (PubMed : 27217402). Converts angiotensin I to angiotensin 1-9, a nine-amino acid peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor angiotensin II (PubMed : 10924499, PubMed : 10969042, PubMed : 11815627, PubMed : 14504186, PubMed : 19021774). Also removes the C-terminal residue from three other vasoactive peptides, neurotensin, kinetensin, and des-Arg bradykinin, but is not active on bradykinin (PubMed : 10969042, PubMed : 11815627). Also cleaves other biological peptides, such as apelins (apelin-13, [Pyr1]apelin-13, apelin-17, apelin-36), casomorphins (beta-casomorphin-7, neocasomorphin) and dynorphin A with high efficiency (PubMed : 11815627, PubMed : 27217402, PubMed : 28293165). In addition, ACE2 C-terminus is homologous to collectrin and is responsible for the trafficking of the neutral amino acid transporter SL6A19 to the plasma membrane of gut epithelial cells via direct interaction, regulating its expression on the cell surface and its catalytic activity (PubMed : 18424768, PubMed : 19185582).. (Microbial infection) Acts as a receptor for human coronaviruses SARS-CoV and SARS-CoV-2, as well as human coronavirus NL63/HCoV-NL63.. Isoform 2. Non-functional as a carboxypeptidase.. Isoform 2. (Microbial infection) Non-functional as a receptor for human coronavirus SARS-CoV-2.

See full target information ACE2

其他靶点

,FGF1,ALB,JAML,ANGPT4,TNFSF13B,CD163,CLU,CRTAM,CXCL14,CST3,DCN,DLL1,AHSG,FOLR1,FURIN,,CSF3R,SPINT2,IL17RB,IL27,LAG3,Low-density lipoprotein receptor,TNFRSF11A,RBP4,SOST,SDC1,TNFRSF13B,TFPI,THBS1,TNFRSF10B,TNFSF11,TNNI2,Urokinase-type plasminogen activator,CDH5,CCN4

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人Cytokine抗体阵列D (40 Targets) - Quantitative

Human Cytokine Antibody Array D (40 Targets) - Quantitative

Multiplex Protein Detection - Human Cytokine Antibody Array D (40 Targets) - Quantitative (AB197441)

Multiplex Protein Detection - Human Cytokine Antibody Array D (40 Targets) - Quantitative (AB197441)

Multiplex Protein Detection - Human Cytokine Antibody Array D (40 Targets) - Quantitative (AB197441)

关键信息

检测类型

反应种属

靶标

检测方法

检测平台

样品类型

产品详情