Anti-Perilipin A+B抗体(ab3527)

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Western blot - Anti-Perilipin A+B antibody (ab3527)

    Key features and details

    • Rabbit polyclonal to Perilipin A+B
    • Suitable for: WB
    • Reacts with: Mouse
    • Isotype: IgG

    概述

    • 产品名称

      Anti-Perilipin A+B抗体

    • 描述

      兔多克隆抗体to Perilipin A+B

    • 宿主

      Rabbit

    • 经测试应用

      适用于: WBmore details

    • 种属反应性

      与反应: Mouse

    • 免疫原

      Synthetic peptide corresponding to Rat Perilipin A+B aa 1-100 (N terminal).

      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • 阳性对照

      • WB: 3T3-L1 cell extract

    • 常规说明

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    性能

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab3527于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    WB
    1/1000.
    说明
    WB
    1/1000.

    靶标

    • 相关性

      Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.

    • 细胞定位

      Lipid droplet

    • 数据库链接

      • 别名

        • Lipid droplet associated protein antibody
        • PERIA antibody
        • PERIB antibody
        • Perilipin A antibody
        • Perilipin antibody
        • Perilipin B antibody
        • PLIN antibody
        see all

      图片

      • Western blot - Anti-Perilipin A+B antibody (ab3527)
        Western blot - Anti-Perilipin A+B antibody (ab3527)
        Anti-Perilipin A+B antibody (ab3527) + Cell extracts prepared from 3T3-L1 cells


        Western blot detection of perilipin A and B in 3T3-L1 cell extract using ab3527.

      文献 (2)

      发表研究结果有使用 ab3527？请让我们知道，以便我们可以引用本数据表中的参考文章。

      ab3527 被引用在 2 文献中.

      • Matushansky I  et al. A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas. Am J Pathol 172:1069-80 (2008). WB ; Human . PubMed: 18310505
      • Fernández-Veledo S  et al. Hyperinsulinemia induces insulin resistance on glucose and lipid metabolism in a human adipocytic cell line: paracrine interaction with myocytes. J Clin Endocrinol Metab 93:2866-76 (2008). PubMed: 18430774

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