PE Anti-CD10抗体[FR4D11/F3] (ab1165)
Key features and details
- PE Mouse monoclonal [FR4D11/F3] to CD10
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
概述
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产品名称
PE Anti-CD10抗体[FR4D11/F3]
参阅全部 CD10 一抗 -
描述
PE小鼠单克隆抗体[FR4D11/F3] to CD10 -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
种属反应性
与反应: Human -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
Preservative: 0.1% Sodium azide
Constituent: 0.5% BSA -
Concentration information loading... -
克隆
单克隆 -
克隆编号
FR4D11/F3 -
骨髓瘤
unknown -
同种型
IgG1 -
轻链类型
unknown -
研究领域
相关产品
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Isotype control
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Recombinant Protein
应用
应用说明
Characterization of leukaemias and lymphomas in human lysed whole peripheral blood or mononuclear cells separated by density gradient.
Childhood ALL prognosis (patients CD10+ have a better prognosis than CD10-).
CD10 (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.
10µl ofCD10 (PE) is sufficient for labelling of 1x106 cells.
Molecular F/P ratio: 1.0
Childhood ALL prognosis (patients CD10+ have a better prognosis than CD10-).
CD10 (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.
10µl ofCD10 (PE) is sufficient for labelling of 1x106 cells.
Molecular F/P ratio: 1.0
靶标
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功能
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. -
序列相似性
Belongs to the peptidase M13 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 4311 Human
- Omim: 120520 Human
- SwissProt: P08473 Human
- Unigene: 307734 Human
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别名
- Atriopeptidase antibody
- CALLA antibody
- CD10 antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab1165 被引用在 2 文献中.
- Husak Z & Dworzak MN CD99 ligation upregulates HSP70 on acute lymphoblastic leukemia cells and concomitantly increases NK cytotoxicity. Cell Death Dis 3:e425 (2012). Flow Cyt ; Human . PubMed: 23152061
- Ferletta M et al. Canine mammary tumors contain cancer stem-like cells and form spheroids with an embryonic stem cell signature. Int J Dev Biol 55:791-9 (2011). PubMed: 22161835