概述

  • 产品名称
  • 描述
    山羊多克隆抗体to PDI
  • 宿主
    Goat
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Orangutan
  • 免疫原

    Synthetic peptide corresponding to Human PDI aa 129-141 (internal sequence) (Cysteine residue). NP_006840.2
    Sequence:

    C-THPEEYTGPRDAE


    Database link: Q13087

  • 阳性对照
    • WB: Human pancreas lysate.

性能

应用

Our Abpromise guarantee covers the use of ab223670 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 58.2 kDa).

靶标

  • 功能
    Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.
  • 组织特异性
    Highly expressed in pancreas (at protein level).
  • 序列相似性
    Belongs to the protein disulfide isomerase family.
    Contains 2 thioredoxin domains.
  • 翻译后修饰
    The disulfide-linked homodimer exhibits an enhanced chaperone activity.
    Glycosylated.
  • 细胞定位
    Endoplasmic reticulum lumen.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Pancreas specific protein disulfide isomerase antibody
    • Pancreas-specific protein disulfide isomerase antibody
    • Pancreatic protein disulfide isomerase antibody
    • PDA2 antibody
    • PDI antibody
    • PDIA2 antibody
    • PDIA2_HUMAN antibody
    • PDIp antibody
    • PDIR antibody
    • Protein disulfide isomerase A2 antibody
    • Protein disulfide isomerase antibody
    • Protein disulfide isomerase associated 2 antibody
    • Protein disulfide isomerase family A member 2 antibody
    • Protein disulfide isomerase pancreatic antibody
    • Protein disulfide-isomerase A2 antibody
    • Rho GDP dissociation inhibitor gamma antibody
    see all

图片

  • Anti-PDI antibody (ab223670) at 0.03 µg/ml + human pancreas lysate at 35 µg

    Developed using the ECL technique.

    Predicted band size: 58.2 kDa
    Additional bands at: 70 kDa (possible glycosylated form)



    Primary incubation was 1 hour.

实验方案

文献

ab223670 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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