PE Anti-p75 NGF Receptor抗体[NGFR5],prediluted (ab157333)
Key features and details
- PE Mouse monoclonal [NGFR5] to p75 NGF Receptor, prediluted
- Suitable for: Flow Cyt
- Reacts with: Rabbit, Cat, Human, Ferret, Non human primates
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
概述
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产品名称
PE Anti-p75 NGF Receptor抗体[NGFR5],prediluted
参阅全部 p75 NGF Receptor 一抗 -
描述
PE小鼠单克隆抗体[NGFR5] to p75 NGF Receptor,prediluted -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Rabbit, Cat, Human, Ferret, Non human primates
不与反应: Mouse, Rat -
免疫原
Purified p75 NGF Receptor protein isolated from Human melanoma cell line A875.
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表位
The epitope is localized within amino acids 1-160. -
阳性对照
- Human blood cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 0.2% BSA, 99% PBS -
Concentration information loading...
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纯度
Size exclusion -
克隆
单克隆 -
克隆编号
NGFR5 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
- APC Anti-p75 NGF Receptor antibody [NGFR5], prediluted (ab176522)
- Anti-p75 NGF Receptor antibody [NGFR5] - BSA and Azide free (ab212682)
- PE/Cy7® Anti-p75 NGF Receptor antibody [NGFR5] (ab234270)
- PerCP/Cy5.5® Anti-p75 NGF Receptor antibody [NGFR5] (ab234446)
- Anti-p75 NGF Receptor antibody [NGFR5] (ab3125)
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab157333于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use 10µl for 106 cells.
10ul per 100ul whole blood. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
说明 |
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Flow Cyt
Use 10µl for 106 cells. 10ul per 100ul whole blood. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. -
序列相似性
Contains 1 death domain.
Contains 4 TNFR-Cys repeats. -
结构域
Death domain is responsible for interaction with RANBP9.
The extracellular domain is responsible for interaction with NTRK1. -
翻译后修饰
N- and O-glycosylated.
O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc.
Phosphorylated on serine residues. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 101101519 Cat
- Entrez Gene: 101680416 Ferret
- Entrez Gene: 4804 Human
- Entrez Gene: 100349095 Rabbit
- Omim: 162010 Human
- SwissProt: P08138 Human
- Unigene: 415768 Human
- Unigene: 681726 Human
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别名
- CD271 antibody
- CD271 antigen antibody
- Gp80 LNGFR antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab157333 被引用在 3 文献中.
- MacKenzie KC et al. The Somatic Mutation Paradigm in Congenital Malformations: Hirschsprung Disease as a Model. Int J Mol Sci 22:N/A (2021). PubMed: 34830235
- Zhao F et al. Programmed cell death 1 correlates with the occurrence and development of MG63 osteosarcoma. Oncol Lett 12:5199-5204 (2016). Flow Cyt ; Human . PubMed: 28105229
- Binder E et al. Enteric neurospheres are not specific to neural crest cultures: implications for neural stem cell therapies. PLoS One 10:e0119467 (2015). PubMed: 25799576