为了使您在Abcam官网的浏览体验更顺畅,请使用最新版本的浏览器比如 Google Chrome

我们使用cookies,使我们网站尽可能对您有帮助。

我们的Cookie政策介绍了您如何能够取消cookie使用。

如果您不改变cookie设置,我们认为您愿意接受cookie。

继续 继续

致电 +86 21 2070 0500 或 联系我们

  • 我的账户
  • 退出
登录 或 注册

欢迎光临

登录 或

您还没有帐户?

注册
我的购物篮
快速订购
Abcam homepage

  • 研究用途的产品
    按产品类型
    一抗
    二抗
    免疫测定试剂盒与试剂
    细胞与组织成像工具
    细胞与生化测定
    蛋白质与肽
    按产品类型
    蛋白质组学工具
    激动剂、活化剂、拮抗剂与抑制剂
    细胞株和裂解液
    多重miRNA检测
    多因子分析试剂盒
    按研究领域
    癌症
    心血管
    细胞生物学
    表观遗传学
    代谢
    发育生物学
    按研究领域
    免疫学
    微生物学
    神经科学
    信号转导
    干细胞
  • 诊断和治疗的解决方案
    定制方案及合作关系

    定制抗体开发及商务合作助力您的诊断和治疗探索。

    与我们一起开创定制方案

    与我们成为伙伴

  • 技术支持
    支持中心

    获取研究建议和支持

    查看支持中心

    Protocols

    一步一步完成您的实验

    查看Protocols

  • 活动通知
    • 会议年历
    • 肿瘤研究
    • 心血管研究
    • 染色质及细胞核信号转导研究
    • 免疫学
    • 神经生物学
    • 干细胞研究
    • 商品展览
    • 实验技术视频
    查看最新活动

    活动说明、摘要提交、演讲者、注册方式及更多信息

    查看全球活动安排

  • 通路
    细胞信号转导通路

    查看所有通路

    查看交叉通路

在新冠疫情期间支持我们的客户和员工–了解更多

Neuroscience Neurotransmitter Neuropeptides Hormones

Anti-Oxytocin-neurophysin 1抗体(ab2078)

  • Datasheet
  • SDS
Reviews (2)Q&A (3)References (14)

Product price, shipping and contact information

Currently unavailable

抱歉,我们目前无法显示此内容。

请联系我们以完成下单,或者之后再尝试访问。

 

正在加载规格和价格。。。

 

送货和订单信息

Abpromise

产品质量保证,客户专家支持,

点击获取更多

Key features and details

  • Rabbit polyclonal to Oxytocin-neurophysin 1
  • Reacts with: Mouse, Rat, Sheep, Rabbit, Human, Pig
  • Isotype: IgG

你可能会感兴趣

一抗
Product image
Anti-FOXP2 antibody - C-terminal (ab1307)
一抗
Product image
Alexa Fluor® 647 Anti-Vinculin antibody [EPR8185] (ab196579)
二抗
Product image
Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

查看更多相关产品

概述

  • 产品名称

    Anti-Oxytocin-neurophysin 1抗体
    参阅全部 Oxytocin-neurophysin 1 一抗
  • 描述

    兔多克隆抗体to Oxytocin-neurophysin 1
  • 宿主

    Rabbit
  • 特异性

    Less than 1% reactivity to vasopressin.
  • 种属反应性

    与反应: Mouse, Rat, Sheep, Rabbit, Human, Pig
  • 免疫原

    Other Immunogen Type corresponding to Oxytocin-neurophysin 1. Immunogen: oxytocin-thyroglobulin

  • 常规说明

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.

    One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.

    Learn more here.

性能

  • 形式

    Liquid
  • 存放说明

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液

    Constituent: Whole serum
  • Concentration information loading...
  • 纯度

    Whole antiserum
  • 克隆

    多克隆
  • 同种型

    IgG
  • 研究领域

    • Neuroscience
    • Neurotransmitter
    • Neuropeptides
    • Hormones
    • Neuroscience
    • Neurology process
    • Neuroendocrinology
    • Oxytocin & Vasopressin

相关产品

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human Oxytocin-neurophysin 1 protein (Tagged) (ab235866)

靶标

  • 相关性

    Neurophysin 1 specifically binds oxytocin. Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Oxytocin contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
  • 细胞定位

    Secreted
  • 数据库链接

    • Entrez Gene: 5020 Human
    • Entrez Gene: 18429 Mouse
    • Entrez Gene: 25504 Rat
    • Omim: 167050 Human
    • SwissProt: P01178 Human
    • SwissProt: P35454 Mouse
    • SwissProt: P01177 Pig
    • SwissProt: P13389 Sheep
    • Unigene: 113216 Human
    • Unigene: 48915 Rat
    see all
  • 别名

    • MGC126890 antibody
    • MGC126892 antibody
    • Neurophysin 1 antibody
    • Neurophysin I antibody
    • Ocytocin antibody
    • OT antibody
    • OT NPI antibody
    • OXT antibody
    • Oxytocin Neurophysin preproprotein antibody
    • Oxytocin prepro (neurophysin I) antibody
    • Oxytocin prepropeptide antibody
    • Oxytocin-neurophysin 1 antibody
    see all

实验方案

  • Immunohistochemistry protocols

Click here to view the general protocols

数据表及文件

  • SDS download

  • Datasheet download

    Download

文献 (14)

发表研究结果有使用 ab2078?请让我们知道,以便我们可以引用本数据表中的参考文章。

ab2078 被引用在 14 文献中.

  • Ogata K  et al. Lavender Oil Reduces Depressive Mood in Healthy Individuals and Enhances the Activity of Single Oxytocin Neurons of the Hypothalamus Isolated from Mice: A Preliminary Study. Evid Based Complement Alternat Med 2020:5418586 (2020). PubMed: 32733584
  • Song TJ  et al. Altered Behaviors and Impaired Synaptic Function in a Novel Rat Model With a Complete Shank3 Deletion. Front Cell Neurosci 13:111 (2019). PubMed: 30971895
  • Mohan S  et al. Oxytocin is present in islets and plays a role in beta-cell function and survival. Peptides 100:260-268 (2018). IF . PubMed: 29274352
  • Zhang B  et al. Central insulin action induces activation of paraventricular oxytocin neurons to release oxytocin into circulation. Sci Rep 8:10415 (2018). PubMed: 29991705
  • Dai D  et al. Direct Involvement of Androgen Receptor in Oxytocin Gene Expression: Possible Relevance for Mood Disorders. Neuropsychopharmacology 42:2064-2071 (2017). PubMed: 28447621
View all Publications for this product

客户评价及客户问答

Show All 评价 Q&A
提交评价 提交问题

1-5 of 5 Abreviews or Q&A

Immunohistochemistry (Frozen sections) abreview for Anti-Oxytocin-neurophysin 1 antibody

Good
Abreviews
Abreviews
abreview image
Application
Immunohistochemistry (Frozen sections)
Sample
Mouse Tissue sections (Brain)
Permeabilization
Yes - 0.1% Triton X-100
Specification
Brain
Blocking step
Serum as blocking agent for 24 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 4°C
Fixative
Paraformaldehyde
Read More

Kevin Zhang

Verified customer

提交于 Jan 31 2018

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) abreview for Anti-Oxytocin antibody

Good
Abreviews
Abreviews
abreview image
Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Blocking step
hydrogen peroxide as blocking agent for 10 minute(s) · Concentration: 3% · Temperature: 25°C
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: citrate, pH6.0, 100C 20 min
Sample
Human Tissue sections (placenta)
Specification
placenta
Permeabilization
No
Fixative
Formaldehyde
Read More

Abcam user community

Verified customer

提交于 Jul 01 2014

Question

Dear ladies and gentleman, I am interestet in the anti-OT and anti-AVP antibodies from this paper: PLoS One. 2011;6(8):e23362. Epub 2011 Aug 17. Oxytocin and vasopressin involved in restraint water-immersion stress mediated by oxytocin receptor and vasopressin 1b receptor in rat brain. Zhao DQ, Ai HB. unfortunately in the refference list of all of your antibodies i couldn´t find this paper, although they had their antibodies from your company. can you please help me?

Read More

Abcam community

Verified customer

Asked on Sep 13 2011

Answer

Thank you for your inquiry. Unfortunately, we are unable to track down the particular antibodies the authors used when it is not specifically mentioned in the paper. However, the following antibodies might have been used: ab39363: anti-Vasopressin (AVP), guaranteed to work in immunohistochemistry (PFA perfusion fixed frozen sections and frozen sections, IHC-FoFr, IHC-Fr) on rat. Click here (or use the following: https://www.abcam.com/Vasopressin-antibody-ab39363.html). ab2078: anti-Oxytocin, guaranteed to work in RIA and immunohistochemistry (PFA perfusion fixed frozen sections and paraffin-embedded sections, IHC-FoFr, IHC-P) on rat. Click here (or use the following: https://www.abcam.com/Oxytocin-neurophysin-1-antibody-ab2078.html). ab11143: anti-Oxytocin, guaranteed to work in immunohistochemistry (frozen sections, IHC-Fr) on rat. Click here (or use the following: https://www.abcam.com/Oxytocin-neurophysin-1-antibody-ab11143.html). ab78364: anti-Oxytocin, guaranteed to work in ELISA and immunohistochemistry (PFA perfusion fixed frozen sections and paraffin-embedded sections, IHC-FoFr, IHC-P) on rat. Click here (or use the following: https://www.abcam.com/Oxytocin-neurophysin-1-antibody-4G11-ab78364.html). We are happy to reassure you that all of our products are covered by our Abpromise, which guarantees that the product will work in the applications and species specified on the datasheet, or we will offer a replacement, credit, or refund within 6 months of purchase. If the product is to be used in an untested species or application, you may be eligible for our testing discount program if the antibody has not yet been purchased. Please contact our Scientific Support team by replying to this email prior to purchase for more information. I hope this information is helpful. Please do not hesitate to contact us again with any other questions.

Read More

Abcam Scientific Support

回复于 Sep 13 2011

Question

I am setting up an RIA to measure oxytocin in rabbit serum and thought your ab 2078 would work. On your website it is listed as having been tested for RIA, do you have a protocol available? Any information regarding this application of ab2078 would be appreciated.

Read More

Abcam community

Verified customer

Asked on Mar 14 2006

Answer

Thank you for your enquiry. I am sorry but we do not have an online RIA protocol. However, I would like to recommmend the following resources: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=716433&dopt=Abstract http://www.phoenixpeptide.com/qcdata/RIK/protocol10-1280_p.pdf http://faculty.washington.edu/jwingfie/protocols.html I hope this information helps, please do not hesitate to contact us if you need any more advice or information.

Read More

Abcam Scientific Support

回复于 Mar 15 2006

Question

Thank you for your quick answer. I know that sometimes antibodies against vasopressin and oxytocin are using for immunostaining of vasotocin and isotocin. I would like to ask you if it's possible to use your antibodies ab8745 (anti-vasopressin) or ab2078 (anti- oxytocin) for vasotocin or isotocin staining? Could you inform me about cross-reaction of ab8745 and ab2078 with vasotocin or isotocin, please.I will be very grateful for your help.

Read More

Abcam community

Verified customer

Asked on Jan 16 2006

Answer

Thank you for your enquiry regarding our antibodies ab2078 and ab8745. Unfortunately we do not have any further information regarding their cross reactivity with vasotocin or isotocin, this has not been tested in our laboratories. I'm very sorry I couldn't help you more on this occasion,

Read More

Abcam Scientific Support

回复于 Jan 16 2006

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

通过邮件收到学术资源和促销信息 注册
研究类别(A-Z)
  • 肿瘤研究
  • 心血管研究
  • 细胞生物学
  • 发育生物学
  • 染色质及细胞核信号转导研究
  • 免疫学
  • 代谢
  • 微生物学
  • 神经生物学
  • 信号转导研究
  • 干细胞研究
产品种类(A-Z)
  • 一抗
  • 二抗
  • 生化试剂
  • 亚类对照
  • 流式细胞仪多色选择器
  • 试剂盒
  • 内参对照
  • 细胞裂解液
  • 多肽
  • 蛋白酶
  • 组织切片
  • 蛋白标签及细胞标记物
  • 相关试剂及工具
帮助与支持
  • 技术支持
  • 技术FAQ
  • 实验步骤与建议
  • 购买FAQ
  • RabMAb 产品
  • 培训课程
  • 按靶标浏览
企业
  • 企业资讯
  • 投资者关系
  • 公司新闻
  • 招贤纳士
  • 关于我们
活动通知
  • 商品展览
  • 会议
全球网站
  • abcam.com
  • abcam.co.jp
QR code for Weechat

微信扫码 关注我们

沪ICP备14046373号-1

沪公网安备 31011502007413号

  • 销售条款
  • 网站使用条款
  • Cookie政策
  • 隐私权政策
  • 法律
© 1998-2021 艾博抗(上海)贸易有限公司版权所有