Anti-OB Cadherin抗体[16G5] (ab151446)
Key features and details
- Mouse monoclonal [16G5] to OB Cadherin
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-OB Cadherin抗体[16G5]
参阅全部 OB Cadherin 一抗 -
描述
小鼠单克隆抗体[16G5] to OB Cadherin -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Extracellular Cadherin domain 1 of OB Cadherin fused to maltose binding protein (P55287).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
16G5 -
骨髓瘤
NS1 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab151446于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/100. Predicted molecular weight: 87 kDa.
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说明 |
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WB
1/100. Predicted molecular weight: 87 kDa. |
靶标
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功能
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. -
组织特异性
Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts. -
疾病相关
Note=A chromosomal aberration involving CDH11 is a common genetic feature of aneurysmal bone cyst, a benign osseous neoplasm. Translocation t(16;17)(q22;p13) with USP6. The translocation generates a fusion gene in which the strong CDH11 promoter is fused to the entire USP6 coding sequence, resulting in USP6 transcriptional up-regulation. -
序列相似性
Contains 5 cadherin domains. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 1009 Human
- Omim: 600023 Human
- SwissProt: P55287 Human
- Unigene: 116471 Human
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别名
- CAD11 antibody
- CAD11_HUMAN antibody
- Cadherin 11 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab151446 被引用在 3 文献中.
- Koike T et al. Altered sulfation status of FAM20C-dependent chondroitin sulfate is associated with osteosclerotic bone dysplasia. Nat Commun 13:7952 (2022). PubMed: 36572689
- Ma C et al. Combined overexpression of cadherin 6, cadherin 11 and cluster of differentiation 44 is associated with lymph node metastasis and poor prognosis in oral squamous cell carcinoma. Oncol Lett 15:9498-9506 (2018). PubMed: 29805672
- Kim C et al. Universal antibody conjugation to nanoparticles using the Fc? receptor I (Fc?RI): quantitative profiling of membrane biomarkers. Bioconjug Chem 25:1893-901 (2014). PubMed: 25215471