Key features and details
- Mouse monoclonal [5C.6] to Nonspecific Cytotoxic Cells
- Reacts with: Rat, Horse, Cow, Dog, Pig, Tilapia, Catfish
- Isotype: IgM
产品名称Anti-Nonspecific Cytotoxic Cells抗体[5C.6]
描述小鼠单克隆抗体[5C.6] to Nonspecific Cytotoxic Cells
种属反应性与反应: Rat, Horse, Cow, Dog, Pig, Tilapia, Catfish
Other Immunogen Type corresponding to Nonspecific Cytotoxic Cells. Purified NCC cells from catfish.
- This antibody as been successfully used in cytotoxic inhibition studies with NCC/NK/LAK cells, panning, and ELISA procedures. In cytotoxicity assays, this antibody is used under saturating conditions to inhibit target cell conjugation.
U.S. Patent Numbers: 5,028,424 and 5,229,494.
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Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
存储溶液Preservative: 0.05% Sodium azide
Constituent: 0.1% BSA
Concentration information loading...
Primary antibody说明Non-specific cytotoxic cells (NCCs) in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. One such property is that NCC/natural killer (NK)/lymphokine activated killer (LAK) cells express spontaneous, non-major histocompatibility complex restricted cytotoxic activity. NCC and LAK lyse a variety of transformed murine and human B-cell, T-cell and myeloid targets. A 32 kDa membrane protein [non-specific cytotoxic cell receptor protein (NCCRP-1)] expressed by NCC and certain mammalian NK/LAK cells mediates this cytotoxicity. NCCRP-1 is evolutionarily conserved and is found in species ranging from marine and freshwater teleosts to higher mammals.
ab2778 被引用在 1 文献中.
- Jaso-Friedmann L et al. NCCRP-1: a novel receptor protein sequenced from teleost nonspecific cytotoxic cells. Mol Immunol 34:955-65 (1997). PubMed: 9464530