Anti-Nonspecific Cytotoxic Cells抗体[5C.6] (ab2778)
Key features and details
- Mouse monoclonal [5C.6] to Nonspecific Cytotoxic Cells
- Suitable for: Inhibition Assay, ELISA, IP, WB, Flow Cyt
- Reacts with: Rat, Horse, Cow, Dog, Pig, Tilapia, Catfish
- Isotype: IgM
概述
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产品名称
Anti-Nonspecific Cytotoxic Cells抗体[5C.6] -
描述
小鼠单克隆抗体[5C.6] to Nonspecific Cytotoxic Cells -
宿主
Mouse -
经测试应用
适用于: Inhibition Assay, ELISA, IP, WB, Flow Cytmore details -
种属反应性
与反应: Rat, Horse, Cow, Dog, Pig, Tilapia, Catfish -
免疫原
Tissue, cells or virus corresponding to Nonspecific Cytotoxic Cells. Purified NCC cells from catfish.
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阳性对照
- This antibody as been successfully used in cytotoxic inhibition studies with NCC/NK/LAK cells, panning, and ELISA procedures. In cytotoxicity assays, this antibody is used under saturating conditions to inhibit target cell conjugation.
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常规说明
U.S. Patent Numbers: 5,028,424 and 5,229,494.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.05% Sodium azide
Constituent: 0.1% BSA -
Concentration information loading...
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纯度
Purified IgM -
Primary antibody说明
Non-specific cytotoxic cells (NCCs) in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. One such property is that NCC/natural killer (NK)/lymphokine activated killer (LAK) cells express spontaneous, non-major histocompatibility complex restricted cytotoxic activity. NCC and LAK lyse a variety of transformed murine and human B-cell, T-cell and myeloid targets. A 32 kDa membrane protein [non-specific cytotoxic cell receptor protein (NCCRP-1)] expressed by NCC and certain mammalian NK/LAK cells mediates this cytotoxicity. NCCRP-1 is evolutionarily conserved and is found in species ranging from marine and freshwater teleosts to higher mammals. -
克隆
单克隆 -
克隆编号
5C.6 -
同种型
IgM -
研究领域
相关产品
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Compatible Secondaries
应用
应用 | Ab评论 | 说明 |
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Inhibition Assay |
Use at an assay dependent concentration.
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ELISA |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
By Western blot, this antibody detects a 32 kDa protein representing nonspecific cytotoxic cell receptor protein. |
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Flow Cyt |
Use at an assay dependent concentration.
ab91545 - Mouse monoclonal IgM, is suitable for use as an isotype control with this antibody. |
说明 |
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Inhibition Assay
Use at an assay dependent concentration. |
ELISA
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. By Western blot, this antibody detects a 32 kDa protein representing nonspecific cytotoxic cell receptor protein. |
Flow Cyt
Use at an assay dependent concentration. ab91545 - Mouse monoclonal IgM, is suitable for use as an isotype control with this antibody. |
实验方案
数据表及文件
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Datasheet download
文献 (1)
ab2778 被引用在 1 文献中.
- Jaso-Friedmann L et al. NCCRP-1: a novel receptor protein sequenced from teleost nonspecific cytotoxic cells. Mol Immunol 34:955-65 (1997). PubMed: 9464530