Anti-Nonspecific Cytotoxic Cells抗体[5C.6] (ab2778)
Key features and details
- Mouse monoclonal [5C.6] to Nonspecific Cytotoxic Cells
- Reacts with: Rat, Horse, Cow, Dog, Pig, Tilapia, Catfish
- Isotype: IgM
概述
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产品名称
Anti-Nonspecific Cytotoxic Cells抗体[5C.6] -
描述
小鼠单克隆抗体[5C.6] to Nonspecific Cytotoxic Cells -
宿主
Mouse -
种属反应性
与反应: Rat, Horse, Cow, Dog, Pig, Tilapia, Catfish -
免疫原
Other Immunogen Type corresponding to Nonspecific Cytotoxic Cells. Purified NCC cells from catfish.
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阳性对照
- This antibody as been successfully used in cytotoxic inhibition studies with NCC/NK/LAK cells, panning, and ELISA procedures. In cytotoxicity assays, this antibody is used under saturating conditions to inhibit target cell conjugation.
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常规说明
U.S. Patent Numbers: 5,028,424 and 5,229,494.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.05% Sodium azide
Constituent: 0.1% BSA -
Concentration information loading...
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纯度
Purified IgM -
Primary antibody说明
Non-specific cytotoxic cells (NCCs) in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. One such property is that NCC/natural killer (NK)/lymphokine activated killer (LAK) cells express spontaneous, non-major histocompatibility complex restricted cytotoxic activity. NCC and LAK lyse a variety of transformed murine and human B-cell, T-cell and myeloid targets. A 32 kDa membrane protein [non-specific cytotoxic cell receptor protein (NCCRP-1)] expressed by NCC and certain mammalian NK/LAK cells mediates this cytotoxicity. NCCRP-1 is evolutionarily conserved and is found in species ranging from marine and freshwater teleosts to higher mammals. -
克隆
单克隆 -
克隆编号
5C.6 -
同种型
IgM -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
实验方案
数据表及文件
文献 (1)
ab2778 被引用在 1 文献中.
- Jaso-Friedmann L et al. NCCRP-1: a novel receptor protein sequenced from teleost nonspecific cytotoxic cells. Mol Immunol 34:955-65 (1997). PubMed: 9464530