Anti-Neurokinin 3 Receptor NK3抗体(ab124025)

概述

  • 产品名称
    Anti-Neurokinin 3 Receptor NK3抗体
    参阅全部 Neurokinin 3 Receptor NK3 一抗
  • 描述
    兔多克隆抗体to Neurokinin 3 Receptor NK3
  • 宿主
    Rabbit
  • 特异性
    ab124025 does not recognise NK1R or NK2R.
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    An 18 amino acid peptide from near the center of Human Neurokinin 3 Receptor NK3.

  • 阳性对照
    • Human brain tissue; RAW 264.7 whole cell lysate
  • 常规说明
    This product should be stored undiluted.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab124025 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 52 kDa).Can be blocked with Neurokinin 3 Receptor NK3 peptide (ab176411).
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.
  • 疾病相关
    Hypogonadotropic hypogonadism 11 with or without anosmia
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 翻译后修饰
    The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MGC148060 antibody
    • MGC148061 antibody
    • Neurokinin B receptor antibody
    • Neurokinin beta receptor antibody
    • Neuromedin K Receptor antibody
    • Neuromedin-K receptor antibody
    • NK 3 receptor antibody
    • NK 3R antibody
    • NK-3 receptor antibody
    • NK-3R antibody
    • NK3 receptor antibody
    • NK3R antibody
    • NK3R_HUMAN antibody
    • NKR antibody
    • TAC 3R antibody
    • TAC3R antibody
    • TAC3RL antibody
    • Tachykinin receptor 3 antibody
    • TACR 3 antibody
    • Tacr3 antibody
    see all

图片

  • Lane 1 : Anti-Neurokinin 3 Receptor NK3 antibody (ab124025) at 0.5 µg/ml
    Lane 2 : Anti-Neurokinin 3 Receptor NK3 antibody (ab124025) at 2 µg/ml

    All lanes : RAW 264.7 whole cell lysate

    Predicted band size: 52 kDa
    Observed band size: 46 kDa (why is the actual band size different from the predicted?)

  • ab124025, at 5µg/ml, staining Neurokinin 3 Receptor NK3 in paraffin-embedded Human brain tissue by Immunohistochemistry.

文献

This product has been referenced in:
  • Vielma AH & Schmachtenberg O Electrophysiological fingerprints of OFF bipolar cells in rat retina. Sci Rep 6:30259 (2016). IHC-P ; Rat . Read more (PubMed: 27457753) »

See 1 Publication for this product

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