Key features and details
- Expression system: Native
- Suitable for: Flow Cyt, Immunomicroscopy
参阅全部 Human Serum Albumin 蛋白酶
蛋白长度Full length protein
偶联物FITC. Ex: 493nm, Em: 528nm
Our Abpromise guarantee covers the use of ab8030 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Fluorochrome/Protein Ratio: 1.5 moles FITC per mole of Human Albumin.
AB8030 contains Polyethylene glycol at 10 mg/mL as a stabilizer.
Concentration information loading...
Shipped at 4°C. Store at 4°C prior to reconstitution. Store at -20°C long term. Avoid freeze / thaw cycle. Reconstitute for long term storage.
Preservative: 0.01% Sodium azide
Constituents: 0.42% Potassium phosphate, 0.87% Sodium chloride, 1% Polyethylene glycol
复溶Reconstitute with 1.0 mL of deionized water
功能Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
疾病相关Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
序列相似性Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains.
翻译后修饰Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab8030 被引用在 5 文献中.
- Zhang SY & Mahler GJ Modelling Renal Filtration and Reabsorption Processes in a Human Glomerulus and Proximal Tubule Microphysiological System. Micromachines (Basel) 12:N/A (2021). PubMed: 34442605
- Offeddu GS et al. An on-chip model of protein paracellular and transcellular permeability in the microcirculation. Biomaterials 212:115-125 (2019). PubMed: 31112823
- Offeddu GS et al. Application of Transmural Flow Across In Vitro Microvasculature Enables Direct Sampling of Interstitial Therapeutic Molecule Distribution. Small 15:e1902393 (2019). PubMed: 31497931
- Zadravec P et al. Development of Recombinant Lactococcus lactis Displaying Albumin-Binding Domain Variants against Shiga Toxin 1 B Subunit. PLoS One 11:e0162625 (2016). ELISA . PubMed: 27606705
- Homan KA et al. Bioprinting of 3D Convoluted Renal Proximal Tubules on Perfusable Chips. Sci Rep 6:34845 (2016). PubMed: 27725720