Native Carcino Embryonic Antigen CEA蛋白(ab742)
Key features and details
- Expression system: Native
- Purity: > 95% >95% by SDS-PAGE
- Suitable for: ELISA
描述
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产品名称
Native Carcino Embryonic Antigen CEA蛋白
参阅全部 CEACAM5 蛋白酶 -
纯度
>95% by SDS-PAGE . -
表达系统
Native -
蛋白长度
Full length protein -
无动物成分
No -
性质
Native
相关产品
技术指标
Our Abpromise guarantee covers the use of ab742 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
ELISA
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形式
Liquid -
补充说明
Blood samples from tissue donors were tested and found negative for HBsAg, HIV-1 and HIV-2 antibodies, HCV.SDS-PAGE denaturating : multiple protein bands 150 – 210 kDa
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: 2% Methyl mannoside
0.1 M PBS
常规信息
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别名
- Carcinoembryonic antigen
- Carcinoembryonic antigen-related cell adhesion molecule 5
- CD66e
see all -
功能
Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. -
组织特异性
Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. -
序列相似性
Belongs to the immunoglobulin superfamily. CEA family.
Contains 7 Ig-like (immunoglobulin-like) domains. -
翻译后修饰
Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate. -
细胞定位
Cell membrane. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (5)
ab742 被引用在 5 文献中.
- Yen YK et al. A Graphene-PEDOT:PSS Modified Paper-Based Aptasensor for Electrochemical Impedance Spectroscopy Detection of Tumor Marker. Sensors (Basel) 20:N/A (2020). PubMed: 32131502
- Liu J et al. Integrating Metal-Enhanced Fluorescence and Surface Acoustic Waves for Sensitive and Rapid Quantification of Cancer Biomarkers from Real Matrices. ACS Sens 3:222-229 (2018). PubMed: 29284267
- Sato M et al. Development and validation of scFv-conjugated affinity silk protein for specific detection of carcinoembryonic antigen. Sci Rep 7:16077 (2017). PubMed: 29167497
- Oberst MD et al. CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas. MAbs 6:1571-84 (2014). PubMed: 25484061
- Li Y et al. Carcinoembryonic antigen interacts with TGF-{beta} receptor and inhibits TGF-{beta} signaling in colorectal cancers. Cancer Res 70:8159-68 (2010). PubMed: 20889724