Anti-N Cadherin抗体(ab76057)
Key features and details
- Rabbit polyclonal to N Cadherin
- Suitable for: IP
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-N Cadherin抗体
参阅全部 N Cadherin 一抗 -
描述
兔多克隆抗体to N Cadherin -
宿主
Rabbit -
特异性
ab76057 does not crossreact with E Cadherin. -
经测试应用
适用于: IPmore details -
种属反应性
与反应: Mouse
预测可用于: Rat, Chicken, Chimpanzee -
免疫原
Unphosphorylated synthetic peptide:
ERPIHAEPQYPVRS
, corresponding to amino acids 811-824 of Human N Cadherin (coupled to a carrier protein). This sequence is conserved in rat and mouse N cadherin, and has three amino acid differences from the conserved region in R Cadherin. -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 50% Glycerol, PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab76057于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IP |
1/100.
|
说明 |
---|
IP
1/100. |
靶标
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功能
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. -
序列相似性
Contains 5 cadherin domains. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 414745 Chicken
- Entrez Gene: 12558 Mouse
- Entrez Gene: 83501 Rat
- SwissProt: P10288 Chicken
- SwissProt: P15116 Mouse
- SwissProt: Q9Z1Y3 Rat
- Unigene: 257437 Mouse
- Unigene: 23200 Rat
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别名
- CADH2_HUMAN antibody
- Cadherin 2 antibody
- Cadherin 2 N cadherin neuronal antibody
see all
图片
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Western blot image of mouse brain lysate immunoprecipitated with no antibody (lane 1), anti-N-Cadherin (CP1751) rabbit polyclonal antibody (lane 2), and whole mouse brain lysate (lane 3). The blot was probed with anti-N-cadherin (Cytoplasmic) mouse monoclonal antibody (lanes 1-3) and detected using anti-Mouse Ig Light Chain specific:HRP secondary antibody.
数据表及文件
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SDS download
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Datasheet download
文献 (196)
ab76057 被引用在 196 文献中.
- Qi C et al. LncRNA NORAD facilitates oral squamous cell carcinoma progression by sponging miR-577 to enhance TPM4. Biol Direct 17:1 (2022). PubMed: 34991683
- Jiang B et al. circEPS15 Overexpression in Hepatocellular Carcinoma Modulates Tumor Invasion and Migration. Front Genet 13:804848 (2022). PubMed: 35211158
- Burgess ER et al. Increased Ascorbate Content of Glioblastoma Is Associated With a Suppressed Hypoxic Response and Improved Patient Survival. Front Oncol 12:829524 (2022). PubMed: 35419292
- Liu M et al. USP18 contributes to the proliferation and migration of ovarian cancer cells by regulating the AKT/mTOR signaling pathway. Acta Biochim Pol 69:417-422 (2022). PubMed: 35696596
- Zhou L et al. Identification and verification of the role of crucial genes through which methionine restriction inhibits the progression of colon cancer cells. Oncol Lett 24:274 (2022). PubMed: 35782898