Anti-Myeloperoxidase抗体[2D4] (ab90810)
Key features and details
- Mouse monoclonal [2D4] to Myeloperoxidase
- Suitable for: ICC/IF
- Reacts with: Rat
- Isotype: IgG1
Related conjugates and formulations
概述
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产品名称
Anti-Myeloperoxidase抗体[2D4]
参阅全部 Myeloperoxidase 一抗 -
描述
小鼠单克隆抗体[2D4] to Myeloperoxidase -
宿主
Mouse -
经测试应用
适用于: ICC/IFmore details
不适用于: IHC-P or WB -
种属反应性
与反应: Rat
预测可用于: Mouse -
免疫原
Full length native protein (purified). This information is proprietary to Abcam and/or its suppliers.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
ab90810 is provided as a 0.2 µm filtered solution. -
克隆
单克隆 -
克隆编号
2D4 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Assay kits
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab90810于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ICC/IF |
1/50.
|
说明 |
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ICC/IF
1/50. |
靶标
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功能
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. -
疾病相关
Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis. -
序列相似性
Belongs to the peroxidase family. XPO subfamily. -
细胞定位
Lysosome. - Information by UniProt
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数据库链接
- Entrez Gene: 17523 Mouse
- Entrez Gene: 303413 Rat
- SwissProt: P11247 Mouse
- Unigene: 4668 Mouse
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别名
- 84 kDa myeloperoxidase antibody
- 89 kDa myeloperoxidase antibody
- EC 1.11.1.7 antibody
see all
图片
实验方案
数据表及文件
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Datasheet download
文献 (19)
ab90810 被引用在 19 文献中.
- Guy R et al. A Novel Rodent Model of Hypertensive Cerebral Small Vessel Disease with White Matter Hyperintensities and Peripheral Oxidative Stress. Int J Mol Sci 23:N/A (2022). PubMed: 35682594
- Wang Y et al. Neutrophil Extracellular Traps (NETs) Promote Non-Small Cell Lung Cancer Metastasis by Suppressing lncRNA MIR503HG to Activate the NF-κB/NLRP3 Inflammasome Pathway. Front Immunol 13:867516 (2022). PubMed: 35707534
- Li JC et al. Neutrophil extracellular traps participate in the development of cancer-associated thrombosis in patients with gastric cancer. World J Gastroenterol 28:3132-3149 (2022). PubMed: 36051331
- Arnold S et al. Single and Multiplex Immunohistochemistry to Detect Platelets and Neutrophils in Rat and Porcine Tissues. Methods Protoc 5:N/A (2022). PubMed: 36136817
- Weng J et al. Augmenter of liver regeneration ameliorates ischemia-reperfusion injury in steatotic liver via inhibition of the TLR4/NF-?B pathway. Exp Ther Med 22:863 (2021). PubMed: 34178136