Anti-MX1抗体(ab95926)
Key features and details
- Rabbit polyclonal to MX1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-MX1抗体
参阅全部 MX1 一抗 -
描述
兔多克隆抗体to MX1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Dog -
免疫原
Recombinant protein fragment corresponding to a region within amino acids 1 and 246 of Human MX1.
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阳性对照
- WB: H1299, HeLa, and Raji whole cell lysate; 293T, A431 and HepG2 whole cell lysate (ab7900) IHC-P: MDA-MB-468 xenograft
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Purified by antigen affinity chromatography. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab95926于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB | (2) |
1/500 - 1/3000. Predicted molecular weight: 76 kDa.
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IHC-P | (6) |
1/100 - 1/500.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 76 kDa. |
IHC-P
1/100 - 1/500. |
靶标
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功能
May regulate the calcium channel activity of TRPCs. Shows activity against influenza virus and VSV, a rhabdovirus. -
序列相似性
Belongs to the dynamin family.
Contains 1 GED domain. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 4599 Human
- Omim: 147150 Human
- SwissProt: P20591 Human
- Unigene: 517307 Human
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别名
- Human interferon regulated resistance GTP binding protein MXA antibody
- IFI 78 antibody
- IFI 78K antibody
see all
图片
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Lane 1 : Anti-MX1 antibody (ab95926) at 1/1000 dilution
Lane 2 : Anti-MX1 antibody (ab95926)
Lane 1 : 293T whole cell lysate/extract
Lane 2 : Human MX-1 transfected 293T cells
Lysates/proteins at 30 µg per lane.
Secondary
All lanes : HRP-conjugated anti-rabbit IgG antibody
Predicted band size: 76 kDa -
Immunohistochemical analysis of paraffin embedded MDA-MB-468 xenograft, using ab95926 at a 1/500 dilution.
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All lanes : Anti-MX1 antibody (ab95926) at 1/5000 dilution
Lane 1 : H1299 cell lysate
Lane 2 : HeLa cell lysate
Lane 3 : Raji cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 76 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (39)
ab95926 被引用在 39 文献中.
- Jurczyszak D et al. ISG15 deficiency restricts HIV-1 infection. PLoS Pathog 18:e1010405 (2022). PubMed: 35333911
- Filipe IC et al. Comparison of tissue tropism and host response to enteric and respiratory enteroviruses. PLoS Pathog 18:e1010632 (2022). PubMed: 35789345
- Zhou M et al. Activation of cGAS-STING pathway - A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune-mediated necrotizing myopathy. J Clin Lab Anal 36:e24631 (2022). PubMed: 36030554
- Pierini V et al. SERINC5 Can Enhance Proinflammatory Cytokine Production by Primary Human Myeloid Cells in Response to Challenge with HIV-1 Particles. J Virol 95:N/A (2021). PubMed: 33597208
- Lepelley A et al. Enhanced cGAS-STING-dependent interferon signaling associated with mutations in ATAD3A. J Exp Med 218:N/A (2021). PubMed: 34387651